Intracranial Infections

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Intracranial Infections trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

RecruitingPhase 2/3

NCT07556991

Prospective Clinical Investigation on Infection as a Cause of Chronic Subdural Hematoma.

Chronic subdural hematoma (cSDH) is a very common disease, primarily affecting older people, and is associated with significant morbidity and mortality. The inc…

Germany164 participantsStarted 2024-09-01

Treatment: Amoxicillin + clavulanic acid, Placebo ( FE)

RecruitingPhase 2

NCT06634069

Study SOLACE SEPSIS

A Pilot, Randomized, Double-Blinded, Controlled Study of Hemodynamic and Acid Base Effects of 0.5M Sodium Lactate and 3% Saline Solutions in Septic Shock Patien…

Czechia40 participantsStarted 2024-11-24

Treatment: Sodium Lactate, 3% NaCl

RecruitingPhase 2

NCT07383649

Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection

This is a phase II trial with an initial safety lead-in evaluating the efficacy, safety, neurocognitive, and quality-of-life outcomes of anti-cytomegalovirus (C…

United States28 participantsStarted 2026-05

Treatment: Valganciclovir

RecruitingNot Applicable

NCT07410624

Augmented Renal Clearance in Neurocritical Care

Stroke, severe brain injury, uncontrolled seizures and brain infections are the most common life-threatening neurological illnesses in the world with an estimat…

United States, Canada512 participantsStarted 2021-10-01

RecruitingPhase 4

NCT07311343

Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia

Project Name: Randomized Controlled Clinical Study on oral hygiene and prophylactic antibiotics to prevent Intracerebral Hemorrhage associated pneumonia Resea…

China440 participantsStarted 2026-01-07

Treatment: wether apply enhanced oral care combined with prophylactic antibiotics

RecruitingPhase 1

NCT05001750

Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

The principal objective of this study is to compare the incidence of ventriculostomy related infections (VRIs) in patients who receive twenty-four hours of anti…

United States84 participantsStarted 2021-06-14

Treatment: Long term (continuous) prophylactic antibiotics, 24 hours antibiotics

All recent trials (56 shown)

TerminatedNot Applicable

NCT04748289

ICU Cockpit Apps: Interventional Study With First ICU Cockpit Software Applications

In neurocritical care, besides the standard intensive care monitoring, even more data are obtained from the very complex pathophysiological changes in brain dis…

Switzerland90 participantsStarted 2021-03-01

Treatment: ICU Cockpit software testing

CompletedNot Applicable

NCT07407972

Effect of Optıc Nerve Dıameter ın Tymphanoplasty Surgery Performed ın Lateral Head Posıtıon

Studies exist to determine the effect of laparoscopic surgical procedures on increased intra-abdominal pressure; these studies include optic nerve sheath diamet…

Turkey (Türkiye)53 participantsStarted 2020-01-01

Treatment: optic nerve diameter

Intracranial Infections

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

Prospective Clinical Investigation on Infection as a Cause of Chronic Subdural Hematoma.

Study SOLACE SEPSIS

Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection

Augmented Renal Clearance in Neurocritical Care

Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia

Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

All recent trials (56 shown)

ICU Cockpit Apps: Interventional Study With First ICU Cockpit Software Applications

Effect of Optıc Nerve Dıameter ın Tymphanoplasty Surgery Performed ın Lateral Head Posıtıon

Trial phase breakdown

Trial status

Actively recruiting — 12 trials

Prospective Clinical Investigation on Infection as a Cause of Chronic Subdural Hematoma.

Study SOLACE SEPSIS

Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection

Augmented Renal Clearance in Neurocritical Care

Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia

Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

All recent trials (56 shown)

ICU Cockpit Apps: Interventional Study With First ICU Cockpit Software Applications

Effect of Optıc Nerve Dıameter ın Tymphanoplasty Surgery Performed ın Lateral Head Posıtıon

Postherpetic Neuralgia After Herpes Zoster and Incident Dementia Risk

Clinical Trial of an Anti-Fog Drainage Device for Endoscopic Endonasal Sellar Region Tumor Surgery

Non-Invasive Monitoring of Traumatic Brain Injury Progression Using the Infrascanner (MOBI-1)

Rural Dementia Caregiver Project

PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)

Concentration Monitoring of Anti-infective Drugs in Human Cerebrospinal Fluid and Its Clinical Application

Epidemiology of Intracerebral Hemorrhage

A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control

Baricitinib for the Lung Injury Following Spontaneous SAH

Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD)

Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomo…

Machine Learning Predictive Models for Sepsis Risk in ICU Patients With Intracerebral Hemorrhage

PatientSpot Formerly Known as ArthritisPower

Hyperglycemia in Neurosurgery

DetectIon of Severe Sepsis In PATients With Neurological haemorrhagE (The DISSIPATE Study)

Role of Imaging in Complications of Sinusitis

Detecting Sepsis in Patients With Severe Subarachnoideal Hemorrhage

Early Ventriculo-peritoneal Shunt in Subarachnoid Patients With External Ventricular Drainage