Infection in ICU

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Infection in ICU trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 29 trials

RecruitingNot Applicable

NCT07300306

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of…

Turkey (Türkiye)2,500 participantsStarted 2026-05-04

RecruitingNot Applicable

NCT07179276

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Sepsis is a dysregulated host response to infection that leads to life-threatening organ dysfunction and represents a major healthcare problem. Septic shock is…

France750 participantsStarted 2026-03-29

Treatment: CO2gap-guided resuscitation strategy

RecruitingNot Applicable

NCT07068022

Organ Dysfunction Score for Obstetric Patients

The goal of this observational study is to develop and evaluate an organ dysfunction score adapted to pregnancy and early puerperium (SOFA-OBS) that also incorp…

Argentina130 participantsStarted 2025-10-06

Treatment: Organ dysfunction score adjusted to obstetric patients (SOFA-OBS)

RecruitingNot Applicable

NCT07542366

The Feasibility of Pulmonary Perfusion Assessment Using Sodium Bicarbonate Contrast With Electrical Impedance Tomography…

The goal of this observational pilot study is to learn if sodium bicarbonate can be used safely and effectively as a contrast agent to map lung blood flow using…

China41 participantsStarted 2024-09-26

RecruitingPhase 3

NCT07530146

Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under…

The study is a prospective randomized controlled trial comparing the efficacy and safety of propofol-ketamine ("Ketofol") versus propofol monotherapy in geriatr…

Egypt41 participantsStarted 2026-04

Treatment: Ketofol, propofol (drug)

RecruitingNot Applicable

NCT07233837

Hydrogen Peroxide and Ultraviolet Light for Disinfecting Surfaces in Intensive Care Units

Healthcare-associated infections (HAIs) remain a major problem in intensive care units (ICUs), driven by environmental contamination with multidrug-resistant or…

Brazil5,000 participantsStarted 2026-01-05

Treatment: Aerosol of hydrogen peroxide, Irradiation of ultraviolet light

All recent trials (100 shown)

Active — Not RecruitingPhase 2

NCT05996835

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)

The purpose of this Ph2b study is to characterize the dose-response relationship and to evaluate the safety and efficacy of three different single doses of TIN8…

United States320 participantsStarted 2024-01-18

Treatment: TIN816 70 mg lyophilisate powder, Placebo

Not Yet RecruitingNot Applicable

NCT06547749

Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections

Acute respiratory infections (ARIs) are among the leading causes of hospitalization, morbidity, and mortality in children worldwide, particularly among critical…

Egypt63 participantsStarted 2026-06

Treatment: Serum 25-Hydroxyvitamin D Assessment

Infection in ICU

Trial phase breakdown

Trial status

Actively recruiting — 29 trials

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Organ Dysfunction Score for Obstetric Patients

The Feasibility of Pulmonary Perfusion Assessment Using Sodium Bicarbonate Contrast With Electrical Impedance Tomography…

Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under…

Hydrogen Peroxide and Ultraviolet Light for Disinfecting Surfaces in Intensive Care Units

All recent trials (100 shown)

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)

Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections

Trial phase breakdown

Trial status

Actively recruiting — 29 trials

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Organ Dysfunction Score for Obstetric Patients

The Feasibility of Pulmonary Perfusion Assessment Using Sodium Bicarbonate Contrast With Electrical Impedance Tomography…

Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under…

Hydrogen Peroxide and Ultraviolet Light for Disinfecting Surfaces in Intensive Care Units

All recent trials (100 shown)

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)

Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections

Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or…

Use of Oxiris Filter in Septic Shock Patients Requiring Renal Replacement Therapy: A Retrospective Cohort Study

ICU Cockpit Apps: Interventional Study With First ICU Cockpit Software Applications

Load Incorporating Cardiac Assessment by Echocardiography In Patients With SEpsis (LIAISE Study)

EARLY Antibiotics aDAptation in Severe Pneumonia(The EARLY ADAPT Study)

Combined Strategy Using Automated Subglottic Secretion Drainage and Continuous Cuff Pressure Monitoring to Prevent Micro…

Innate Immune Immunoparalysis and Ventilator-Associated Pneumonia in Critically Ill Elderly Patients

The Effect of an Suction Toothbrush on the Development of Ventilator-Associated Pneumonia

Investigation of the Relationship Between MD, MLR and NLR With APRs in Sepsis in the ICU

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and…

Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catechola…

Efficacy & Cost Effectiveness of Antimicrobial-impregnated CVCs in CLABSI Prevention in a Malaysia Adult ICU

Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A…

Artificial Intelligence-Based Evaluation of Chest X-Rays in Ventilator-Associated Pneumonia

Prospective Observational Trial of IAPA

Long-term Assessment of Patients Treated in the ICU for Sepsis

Quantifying Gram-negative Resistance to Empiric Therapy in the Intensive Care Unit

Systemic Immune-Inflamation Index and Mortality in ICU Patients