Heterozygous or Homozygous Familial Hypercholesterolemia

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Heterozygous or Homozygous Familial Hypercholesterolemia trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 3

NCT05682378

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION…

The purpose of this open-label, single arm, multicenter extension study is to evaluate the long-term safety and tolerability of inclisiran in participants with…

United States195 participantsStarted 2023-02-10

Treatment: Inclisiran

All recent trials (3 shown)

CompletedPhase 3

NCT02624869

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Ch…

The main purpose of this study is to describe the safety and tolerability of 80 weeks of subcutaneous (SC) evolocumab when added to standard of care in children…

United States, Australia, Austria163 participantsStarted 2016-09-10

Treatment: Evolocumab

CompletedPhase 3

NCT00694109

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With F…

To evaluate the safety and efficacy of extended dosing with mipomersen (ISIS 301012) in participants with familial hypercholesterolemia or severe hypercholester…

United States144 participantsStarted 2008-04

Treatment: Mipomersen Sodium