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Hepatic Impairment
Clinical trial pipeline · Data from ClinicalTrials.gov
See which Hepatic Impairment trials may be worth asking aboutClinical trial pipeline · Data from ClinicalTrials.gov
See which Hepatic Impairment trials may be worth asking aboutNorth America
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This trial is intended to understand how the body processes repinatrabit in people with moderate liver impairment and severe kidney impairment and also to compa…
The primary purpose of the study is to determine the effect of mild, moderate, and severe hepatic impairment on the PK of total treprostinil palmitil (TP) and t…
The objective of this study is to investigate the PK, PD, safety, and tolerability of ivosidenib in adult participants with IDH1-mutated malignancies and hepati…
This study is open to adults aged between 18 and 80 years of age with a body mass index (BMI) of 18.5 to 42 kg/m². People with or without liver problems can tak…
This open-label study will evaluate the effect on the pharmacokinetics (PK), safety, and tolerability of a single oral dose of inavolisib in participants with m…
The purpose of this study is to examine the safety and tolerability of AZD6234 and AZD9550 in participants with hepatic impairment and participants with normal…
This trial adopts a single-center, single-dose, open-label, non-randomized, parallel-controlled design. It will be conducted in participants with varying degree…
The goal of this clinical trial is to learn how liver cirrhosis affects the way the body processes drugs in adults with different stages of liver cirrhosis. Thi…