Fossa Ependymoma

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Fossa Ependymoma trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 2

NCT07226453

Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

This is a multi-site study of the pharmacodynamic effects and efficacy of metformin in children and young adults with recurrent or progressive Posterior Fossa G…

United States30 participantsStarted 2026-05-05

Treatment: Metformin, Planned Surgical Resection

All recent trials (8 shown)

Not Yet RecruitingPhase 1/2

NCT07567469

A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressiv…

This study is researching an experimental drug called cemiplimab (called "study drug") and the combination of experimental drugs of fianlimab and cemiplimab (ca…

Location not specified120 participantsStarted 2026-08-31

Treatment: Cemiplimab, Cemiplimab+Fianlimab Fixed Dose Combination (FDC)

Active — Not RecruitingPhase 1

NCT02774421

Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma

This study plans to detect the presence of trastuzumab by mass spectroscopy in relapsed posterior fossa ependymoma (PFEPN) tumor specimen pre-treated with a sin…

United States33 participantsStarted 2017-06-12

Treatment: Trastuzumab after SubQ GM-CSF, Trastuzumab in combination with SubQ GM-CSF

Fossa Ependymoma

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

All recent trials (8 shown)

A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressiv…

Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

All recent trials (8 shown)

A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressiv…

Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma

Infusion of 5-Azacytidine (5-AZA) Into the Fourth Ventricle in Patients With Recurrent Posterior Fossa Ependymoma

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

Combination Intraventricular Chemotherapy Pilot Study: 5-Azacytidine (5-AZA) and Trastuzumab Infusions Into the Fourth V…

Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors

Infusion of 5-Azacytidine (5-AZA) Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Ependymoma