Epidermolysis Bullosa Simplex Dowling Meara

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Epidermolysis Bullosa Simplex Dowling Meara trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 2

NCT07027345

A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis…

This Phase II clinical study will assess the efficacy, safety and tolerability of topical TolaSure Gel in adults and pediatric patients (4 years of age and olde…

United States40 participantsStarted 2025-09

Treatment: 5% TolaSure Topical Gel, Topical Placebo Gel

All recent trials (3 shown)

CompletedPhase 1

NCT05062070

Safety and Efficacy of Topical TolaSure Targeting Aggregated Mutant Keratin in Severe Epidermolysis Bullosa Simplex

TolaSure is a topical gel for the promotion of accelerated wound healing. This Phase I study will assess the safety, tolerability, and clinical effects of TolaS…

United States6 participantsStarted 2022-05-05

Treatment: TolaSure Topical Gel, Vehicle Topical Gel

CompletedNot Applicable

NCT01556308

Study of Inflammatory Mechanisms in Epidermolysis Bullosa Simplex- Dowling Meara

Introduction: Epidermolysis Bullosa Simplex-Dowling-Meara (DM-EBS) is a rare genodermatosis characterized by spontaneous or post traumatic large cutaneous blist…

France6 participantsStarted 2012-03

Treatment: Taking of liquid and top of blisters