CYP2D6 Polymorphism

Clinical trial pipeline · Data from ClinicalTrials.gov

See which CYP2D6 Polymorphism trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingNot Applicable

NCT07078227

Long-term Follow-up of Depressive Disorders in Psychiatric Care

The project investigates long-term prognosis and predictors of treatment outcomes for difficult-to-treat depression in patients in secondary psychiatric care. T…

Sweden415 participantsStarted 2025-06-01

Treatment: No intervention is used.

All recent trials (33 shown)

CompletedNot Applicable

NCT06939608

Kinetics of Yohimbine in Humans to Explore Sex and CYP2D6 Genotype Interactions

This study investigates the pharmacokinetics of yohimbine in women and men aged 18 to 40 years to explore sex-specific differences in CYP2D6-dependent drug meta…

Germany36 participantsStarted 2025-04-28

Treatment: Yohimbine, ¹³C₃-caffeine

Active — Not RecruitingNot Applicable

NCT06814652

The Impact of CYP2D6 Polymorphism on Tramadol Pharmacodynamics

CYP2D6 is an enzyme involved in the hepatic metabolism of many clinically important drugs: antiarrhythmics, antidepressants, antipsychotics, β-blockers, and ana…

Iraq40 participantsStarted 2024-09-22

Treatment: Trodon® Hemofarm

CYP2D6 Polymorphism

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Long-term Follow-up of Depressive Disorders in Psychiatric Care

All recent trials (33 shown)

Kinetics of Yohimbine in Humans to Explore Sex and CYP2D6 Genotype Interactions

The Impact of CYP2D6 Polymorphism on Tramadol Pharmacodynamics

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Long-term Follow-up of Depressive Disorders in Psychiatric Care

All recent trials (33 shown)

Kinetics of Yohimbine in Humans to Explore Sex and CYP2D6 Genotype Interactions

The Impact of CYP2D6 Polymorphism on Tramadol Pharmacodynamics

Effects of Isotretinoin on CYP2D6 Activity

Effects of Retinoids on CYP2D6 Activity During Pregnancy

Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol

Metabolites of Tramadol in the Postoperative Surgical Patients

Biological Response to Tamoxifen (TAM) in Patients With Breast Cancer Non Metastatic RH+

Biomarkers of P. Vivax Relapse

CYP2D6 Polymorphism in Patients of General Practice in Austria

Impact of Genetic Polymorphism on Drug-Drug Interactions Involving CYP2D6

Precision Medicine Guided Treatment for Cancer Pain

OPAL: "Opiates and PhArmacoLogy"

A Study to Evaluate Exemestane Tablets Combined With Ovarian Function Suppression/Ablation in Treatment of Premenopausal…

Cytochrome P450's Pharmacogenomics in Chronic Pain Patients

Response to Donepezil, Drug Plasma Concentration and the CYP2D6 and APOE Genetic Polymorphisms

Clozapine Plasma Levels and the Relationship to the Genetic Polymorphism in Shizophrenic Patients

CYP2D6 Screening for Adverse Drug Reactions to Codeine in Breast Milk

A Pilot Study of Varying Doses of Tamoxifen in the Setting of Genetic Polymorphisms of CYP2D6

YouScript IMPACT Registry

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM