Corneal Transplant Failure

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Corneal Transplant Failure trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

RecruitingPhase 2

NCT06753916

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

The main objective of this study is to determine the safety of Ex Vivo Cross Linking (CXL) of donor corneal tissue in participants who have undergone high-risk…

United States96 participantsStarted 2025-04-01

Treatment: Corneal Donor Tissue with Cross Linking, Corneal Donor Tissue without Cross Linking

RecruitingNot Applicable

NCT05847387

The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study

The purpose of this international cohort study is to validate a new method for preoperative assessment of endothelial viability in donor corneal tissues for tra…

Belgium, Germany, Italy135 participantsStarted 2023-12-01

Treatment: V-Check

All recent trials (14 shown)

Not Yet RecruitingPhase 1

NCT06926478

Subconjunctival Humira for Boston Keratoprosthesis

This trial is studying the safety and tolerability of receiving an injection of adalimumab (Humira) during the Boston Keratoprosthesis (KPro) surgery.

United States8 participantsStarted 2026-06-01

Treatment: Adalimumab Injection

Not Yet RecruitingNot Applicable

NCT07344168

EndoArt® Implantation in Subjects With Chronic Corneal Edema - US Study

The EndoArt® device is intended to treat patients with chronic corneal edema due to endothelial dysfunction, in whom prior multiple keratoplasty (EK/PK) have fa…

Location not specified123 participantsStarted 2026-05-01

Treatment: The EndoArt® (Corneal Artificial Endothelial layer)

Corneal Transplant Failure

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study

All recent trials (14 shown)

Subconjunctival Humira for Boston Keratoprosthesis

EndoArt® Implantation in Subjects With Chronic Corneal Edema - US Study

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study

All recent trials (14 shown)

Subconjunctival Humira for Boston Keratoprosthesis

EndoArt® Implantation in Subjects With Chronic Corneal Edema - US Study

Developing a Nationwide Registry to Track Longitudinal Clinical Outcomes of Corneal Surgery and Disease

Cultivated Limbal Epithelial Transplantation (CLET) for Limbal Stem Cell Deficiency (LSCD)

Risk Factors for Human Corneal Graft Failure : a Monocentric Retrospective Observational Cohort

A Multi-Center Study of the Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Defining the Operating Parameters for a Rebound-esthesiometer

Phase 1 Study to Evaluate the Safety and Tolerability of EO1404 in the Treatment of Corneal Edema

Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions

Study to Assess LX201 for Prevention of Corneal Allograft Rejection or Graft Failure in Subjects Who Have Experienced On…

Study to Assess the Efficacy and Safety of LX201 for Prevention of Corneal Allograft Rejection Episodes and Graft Failur…