CLDN18.2-positive Advanced Biliary Tract Cancer

Clinical trial pipeline · Data from ClinicalTrials.gov

See which CLDN18.2-positive Advanced Biliary Tract Cancer trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 2

NCT07450976

A Study of SHR-A1904 in Previous Systemic Treatment Failed Biliary Tract Cancer

This is a multicenter, Phase 2 clinical trial to evaluate the efficacy and safety, PK and immunogenicity of SHR-A1904 in patients with advanced or metastatic bi…

China151 participantsStarted 2026-03-25

Treatment: SHR-A1904 for Injection

All recent trials (4 shown)

Active — Not RecruitingPhase 1/2

NCT05994001

Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standar…

In this clinical study, we will evaluate the efficacy and safety of cardonilimumab (PD1 monoclonal antibody and CTLA-4 monoclonal antibody bisspecific antibodie…

China78 participantsStarted 2023-08-01

Treatment: cardonilizumab, LM-302

Not Yet RecruitingPhase 2

NCT07151872

Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer

This is an open-label, multicenter Phase II clinical study aimed at evaluating the efficacy, safety, PK profile, and immunogenicity of QLS31905 for Injection co…

Location not specified120 participantsStarted 2025-09

Treatment: QLS31905 for Injection, Gemcitabine Hydrochloride for Injection

CLDN18.2-positive Advanced Biliary Tract Cancer

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

A Study of SHR-A1904 in Previous Systemic Treatment Failed Biliary Tract Cancer

All recent trials (4 shown)

Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standar…

Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

A Study of SHR-A1904 in Previous Systemic Treatment Failed Biliary Tract Cancer

All recent trials (4 shown)

Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standar…

Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer

TST001 in Patients With CLDN18.2 Positive Previously Treated Advanced Biliary Tract Cancer