Circulatory Shock

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Circulatory Shock trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 47 trials

RecruitingNot Applicable

NCT05928767

Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted…

The aim of the study is to demonstrate that "frail" patients, defined as having a CFS score greater than or equal to 5, and "severely" frail patients, defined a…

France200 participantsStarted 2023-08-21

RecruitingNot Applicable

NCT07032987

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Sedation (painkillers and sedative drugs) treats pain, reduces suffering, and helps patients in the intensive care unit (ICU) receiving extracorporeal membrane…

United Kingdom120 participantsStarted 2025-11-24

Treatment: Not an intervention study

RecruitingPhase 2

NCT05817851

Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.

Among patients admitted after an out-of-hospital cardiac arrest (OHCA) in intensive care unit (ICU), almost two thirds of patients will develop in the first hou…

France234 participantsStarted 2023-12-27

Treatment: Vitamin C (Laroscorbine) + Vitamin B1 (Bevitine), standard treatment

RecruitingNot Applicable

NCT07300306

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of…

Turkey (Türkiye)2,500 participantsStarted 2026-05-04

RecruitingNot Applicable

NCT07511751

COMPARISON OF THREE TREATMENT MODALITIES IN MYOFASCIAL PAIN SYNDROME

This study aims to compare the effectiveness of dry needling, extracorporeal shock wave therapy (ESWT), and pulsed radiofrequency (PRF) in patients with chronic…

Turkey (Türkiye)60 participantsStarted 2026-03-10

Treatment: Dry Needling, Extracorporeal Shock Wave Therapy

RecruitingNot Applicable

NCT05298124

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

Mitral regurgitation may be seen in the setting of cardiogenic shock. Transcatheter edge-to-edge repair (TEER) has been shown to improve outcomes in patients wi…

United States, Canada144 participantsStarted 2022-05-26

Treatment: Transcatheter edge-to-edge repair, Medical therapy

All recent trials (100 shown)

Active — Not RecruitingNot Applicable

NCT06433596

Autologous PRP and Focal Shock Waves for Erectile Dysfunction

The goal of this clinical trial is to learn if Platelet-rich plasma (PRP) combined with Shock-wave therapy (SWT) works to treat moderate or mild to moderate ere…

Spain116 participantsStarted 2024-05-06

Treatment: Platelet-rich plasma, Shock waves therapy

Not Yet RecruitingNot Applicable

NCT07499128

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event

Background: Drugs or cell therapies to treat cancer can sometimes cause cytokine release syndrome (CRS). That is, the body makes too many cytokines after treat…

United States136 participantsStarted 2026-05-13

Treatment: TempTraq, VitalTraq

Circulatory Shock

Trial phase breakdown

Trial status

Actively recruiting — 47 trials

Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted…

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

COMPARISON OF THREE TREATMENT MODALITIES IN MYOFASCIAL PAIN SYNDROME

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

All recent trials (100 shown)

Autologous PRP and Focal Shock Waves for Erectile Dysfunction

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event

Trial phase breakdown

Trial status

Actively recruiting — 47 trials

Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted…

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

COMPARISON OF THREE TREATMENT MODALITIES IN MYOFASCIAL PAIN SYNDROME

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

All recent trials (100 shown)

Autologous PRP and Focal Shock Waves for Erectile Dysfunction

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event

Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or…

Venous to Arterial Carbon Dioxide Difference (P₍ᵥ-ₐ₎CO₂): Predictor of Septic Patient Prognosis Depending on the ScvO₂

Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors

Fluid Balance Guided by Modified Venous Excess Ultrasonography Versus Standard Care in Patients With Acute Kidney Injury…

Comparison of Extracorporeal Shock Wave Therapy and Low-Level Laser Therapy in Patients With Lateral Epicondylitis

Restoring Sinus Rhythm Using Dual-Shock Technique in Patients With Atrial Fibrillation

Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic Shock

Augmented Pacing for Shock in the Cardiac Intensive Care Unit

Use of Oxiris Filter in Septic Shock Patients Requiring Renal Replacement Therapy: A Retrospective Cohort Study

GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study

Protocolised Early De-Resuscitation in Septic Shock (REDUCE)

Catheter-Oriented Unloading and Recovery With a Left Ventricular Assist Gear: Efficacy in Post Cardiotomy Cardiogenic Sh…

Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance

Platelet Function and Impella Support

Impact of Systematic Point-of-Care Ultrasound Implementation on Clinical Outcomes and Survival in Septic Shock: A Retros…

Hemodynamic and Respiratory Instability During Percutaneous Pulmonary Thrombectomy

Anti-arrhythmic Therapy vs Catheter Ablation as First Line Treatment for AICD Shock Prevention

Radial Pressure Wave Therapy With or Without Parameter Modulation for Carpal Tunnel Syndrome.