Autosomal Dominant Retinitis Pigmentosa

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Autosomal Dominant Retinitis Pigmentosa trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingPhase 1/2

NCT07408232

A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)

This integrated Ph1/2 clinical study is to assess the safety, tolerability and pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of OCT-980 in healthy v…

Australia50 participantsStarted 2026-02-09

Treatment: Phase 1a: OCT-980 Capsule, Phase 1a: Placebo Capsule

RecruitingNot Applicable

NCT01793168

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, i…

United States, Australia20,000 participantsStarted 2010-07

RecruitingNot Applicable

NCT03011541

Stem Cell Ophthalmology Treatment Study II

This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.

United States, Austria, United Arab Emirates500 participantsStarted 2016-01

Treatment: Arm 1

All recent trials (11 shown)

Active — Not RecruitingNot Applicable

NCT06323772

Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa

The aim of the study is to apply a novel clinical investigation protocol in patients with Phosphodiesterase 6A (PDE6A), PDE6B and Rhodopsin (RHO)-based retiniti…

Germany40 participantsStarted 2023-11-17

Active — Not RecruitingPhase 1/2

NCT05203939

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis

This is a Phase 1/2 Study to Assess the Safety and Efficacy of OCU400 in patients with retinitis pigmentosa associated with NR2E3 and RHO mutations and in patie…

United States22 participantsStarted 2022-01-24

Treatment: OCU400 Low Dose, OCU400 Med Dose

Autosomal Dominant Retinitis Pigmentosa

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Stem Cell Ophthalmology Treatment Study II

All recent trials (11 shown)

Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Stem Cell Ophthalmology Treatment Study II

All recent trials (11 shown)

Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis

A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due…

Observational Natural History Study of Autosomal Dominant Retinitis Pigmentosa (adRP)

Trial of Oral Valproic Acid for Retinitis Pigmentosa

Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 6…

Autosomal Dominant Retinitis Pigmentosa: Prevalence of Known Genes Identification of New Loci / Genes

Transcorneal Electrical Stimulation Therapy for Retinal Disease