Advanced Rare Malignant Solid Neoplasm

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Advanced Rare Malignant Solid Neoplasm trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 1/2

NCT07070232

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alon…

This study will evaluate the safety, efficacy, optimal dose, and pharmacokinetics (PK) of BNT326 as monotherapy (Part 1) and as combination treatment with immun…

United States980 participantsStarted 2025-08-12

Treatment: BNT326, Pumitamig

All recent trials (8 shown)

Active — Not RecruitingPhase 2

NCT06303167

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

This phase II MATCH treatment trial evaluates the effectiveness of osimertinib (AZD9291) in treating patients with cancer that has certain genetic changes calle…

United States19 participantsStarted 2016-01-08

Treatment: Biopsy Procedure, Biospecimen Collection

Active — Not RecruitingPhase 2

NCT04969887

Combination Immunotherapy in Rare Cancers Under InvesTigation

The four tumour streams that will be studied in this protocol are based on immunotherapy sensitive rare cancers from CA209-538 which will be further investigate…

Australia240 participantsStarted 2021-08-03

Treatment: Ipilimumab, Nivolumab

Advanced Rare Malignant Solid Neoplasm

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alon…

All recent trials (8 shown)

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

Combination Immunotherapy in Rare Cancers Under InvesTigation

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alon…

All recent trials (8 shown)

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

Combination Immunotherapy in Rare Cancers Under InvesTigation

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Rare Tumor Focused Platform Study of Innovative Therapies and Technologies (PLATFORM2)

Testing the Combination of Anti-cancer Drugs Atezolizumab and Tiragolumab in People With Advanced Stage Rare Cancers, RA…

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers,…

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene