Acute Hyponatremia

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Acute Hyponatremia trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 4

NCT07189091

CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS

This study is enrolling adult patients who require a prolonged stay in the intensive care unit (ICU). These patients often receive large amounts of intravenous…

Belgium640 participantsStarted 2025-10-07

Treatment: Glucose 5% for fluid creep, NaCl 0.9% (normal saline) for fluid creep

All recent trials (12 shown)

CompletedPhase 2

NCT00664014

A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia

This is a randomized, double-blind, multicenter, placebo-controlled (standard therapy + placebo), phase 2 efficacy and safety study of the Tolvaptan tablets in…

China241 participantsStarted 2008-05

Treatment: Tolvaptan, Placebo

TerminatedPhase 4

NCT02959411

Tolvaptan for Advanced or Refractory Heart Failure

This study will clarify the clinical usefulness of Tolvaptan therapy in patients with complicated acute decompensated heart failure and hyponatremia (low blood…

Canada9 participantsStarted 2016-10

Treatment: Tolvaptan, Standard of care diuretic therapy

Acute Hyponatremia

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS

All recent trials (12 shown)

A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia

Tolvaptan for Advanced or Refractory Heart Failure

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS

All recent trials (12 shown)

A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia

Tolvaptan for Advanced or Refractory Heart Failure

Sodium Management in Acute Neurological Injury

Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances

Dietary Sodium Intake in Acute Heart Failure

Tolvaptan for Patients With Acute Neurological Injuries

Bipolar Versus Monopolar Resection of Benign Prostate Hyperplasia

Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)

Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia

THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation

International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With…