Severe Burns

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Severe Burns trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 8 trials

RecruitingPhase 2

NCT06469970

Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults

This is a prospective, observational, monocentric, phase II (exploratory) cohort study aiming to describe the evolutionary profile of the initial volume of gluc…

France15 participantsStarted 2024-11-28

Treatment: Glucose 30% Intravenous Solution

RecruitingPhase 4

NCT07465432

Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn Injuries

Cefiderocol is a powerful, broad spectrum antibiotic approved to treat hospital-acquired or ventilator associated pneumonia and urinary tract infections. Althou…

United States12 participantsStarted 2026-02-16

Treatment: Cefiderocol

RecruitingNot Applicable

NCT04264065

Albumin and Prognosis of Severely Patients Burns

Hemodynamic management has long been identified as a key factor affecting burn prognosis. However, large amounts of crystalloid infusion have been associated wi…

France200 participantsStarted 2022-09-16

RecruitingNot Applicable

NCT07329595

Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury

The aim of this study is to longitudinally monitor dynamic changes in the gut microbiome following severe burn injury using fecal samples. Under standard nutrit…

Hungary30 participantsStarted 2023-12-01

RecruitingPhase 3

NCT06968559

Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns

Burns affect more than 11 million people worldwide each year. These injuries are responsible for severe morbidity resulting in a high societal burden and accoun…

France478 participantsStarted 2025-11-07

Treatment: Dexamethasone, Placebo

RecruitingNot Applicable

NCT07060560

Presepsin Diagnostic Performance in Severe Burn Sepsis

This study enrolls approximately 270 adult patients with severe burns covering at least 20% of total body surface area to evaluate how well the blood biomarker…

South Korea138 participantsStarted 2025-05-01

All recent trials (100 shown)

TerminatedPhase 2

NCT03313076

Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury

The goal of this study is to develop a safe, effective, and readily available treatment that will prevent chronic pain following Major Thermal Burn Injury (MThB…

United States24 participantsStarted 2018-07-19

Treatment: Omega-3 fatty acids (fish oil), Vitamin D3 (cholecalciferol)

Active — Not RecruitingNot Applicable

NCT05423613

Microneedling for Burn Hypertrophic Scars

Approximately 33 to 91% of severe burn victims will develop hypertrophic scars. Hypertrophic scars are defined as erythematous (red), raised and rigid scars tha…

Canada36 participantsStarted 2021-01-22

Treatment: Microneedling

Severe Burns

Trial phase breakdown

Trial status

Actively recruiting — 8 trials

Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults

Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn Injuries

Albumin and Prognosis of Severely Patients Burns

Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury

Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns

Presepsin Diagnostic Performance in Severe Burn Sepsis

All recent trials (100 shown)

Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury

Microneedling for Burn Hypertrophic Scars

Trial phase breakdown

Trial status

Actively recruiting — 8 trials

Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults

Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn Injuries

Albumin and Prognosis of Severely Patients Burns

Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury

Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns

Presepsin Diagnostic Performance in Severe Burn Sepsis

All recent trials (100 shown)

Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury

Microneedling for Burn Hypertrophic Scars

The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients

Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns

Treatment of Severe Ocular Chemical Burns by Subconjunctival Injection of Allogeneic Mesenchymal Stem Cells: An Open-Lab…

Optimizing Fluid Resuscitation in Adults With Major Burns: A Randomized Trial of Burn Navigator™ Versus Parkland Formula

REAnimation Low Immune Status Markers

Vitamin D Deficiency in Adults Following a Major Burn Injury

Association of Continuous Renal Replacement Therapy With Mortality and Length of Stay in Critically Burned Patients

Microbiota in Children With Severe Burn Injury

Strategy to Avoid Excessive Oxygen in Major Burn Patients

Inflammatory Consequences of Crystalloids in Severely Burned Patients

Predictive Role of Glucose/Potassium Ratio on Mortality in Major Burns.

Timing of Surgery And Outcome in Burn Patients ( EARLYBURN )

STAT: Standard Therapy Plus Active Therapy

Organ Protective Effect of Cetirizine In Patients With Severe Burns

Kinesiotaping Versus Pressure Garments on Secondary Upper Extremity Lymphedema.

Evaluation of Safety and Efficacy of realSKIN® (Skin Xenotransplant) for Complete Closure of Severe Burn Wounds

Aquatic Training in Patients With Severe Scarring

Retrospective Analysis of Spray Skin Treats for Severe Burns