Physiologically Based Pharmacokinetic

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Physiologically Based Pharmacokinetic trials may be worth asking about

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingNot Applicable

NCT06042803

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk

The goal of this observational study is to determine the concentration of medicines in human milk during maternal medicine intake. The main questions it aims to…

Belgium30 participantsStarted 2023-02-01Updated 2025-02-27

Treatment: Human milk collection, Optionally: maternal blood sample

All recent trials (8 shown)

CompletedPhase 1

NCT06306391

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

This is a phase I interventional clinical trial and the aim will be to characterize the PK and PD of two formulations of naloxone (intranasal and intravenous) i…

Spain8 participantsStarted 2024-03-05Updated 2026-05-06

Treatment: Intravenous naloxone, Intranasal naloxone

CompletedPhase 1

NCT07223450

A Study on Oral and Intranasal Forms of Oxycodone in Healthy Volunteers Using Pharmacokinetic Modeling

This is a single-dose, 2-period, 2-sequence, fasting, open label, crossover randomized design, comparing the pharmacokinetics (PK) and pharmacodynamics (PD) of…

Spain8 participantsStarted 2025-06-12Updated 2026-05-06

Physiologically Based Pharmacokinetic

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk

All recent trials (8 shown)

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

A Study on Oral and Intranasal Forms of Oxycodone in Healthy Volunteers Using Pharmacokinetic Modeling

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk

All recent trials (8 shown)

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

A Study on Oral and Intranasal Forms of Oxycodone in Healthy Volunteers Using Pharmacokinetic Modeling

Antithrombotics' Therapeutic Optimization in Hospitalized Patients Using Physiologically- and Population-based Pharmacok…

PBPK Modelling Applied to Acetaminophen Poisoned Obese Children

Midazolam Whole Body Physiologically Based Pharmacokinetic Model

Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers

Impact of Thermal Stress on Pulmonary Absorption and Toxicokinetics of 3 Organic Solvents