Lower Extremity or Diabetic Foot Ulcers

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Lower Extremity or Diabetic Foot Ulcers trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

RecruitingNot Applicable

NCT06938685

Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers

This is a randomized controlled crossover trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in trea…

United States132 participantsStarted 2025-10-06

Treatment: Standard of Care, NeoThelium FT

RecruitingNot Applicable

NCT07039396

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Diabetic Foot Ulcers

This is a prospective case series evaluating the efficacy and safety of NeoThelium FT Amnion Skin Graft in the Mangement of Diabetic Foot Ulcers

United States10 participantsStarted 2025-08-26

Treatment: NeoThelium FT (HCT/P 361)

RecruitingNot Applicable

NCT06449638

Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs

The purpose of this study is to evaluate the efficacy of four dehydrated complete human placental membrane, also defined as Cellular, Acellular, Matrix-like Pro…

United States272 participantsStarted 2024-07-16

Treatment: Standard of Care, Revita

RecruitingNot Applicable

NCT06939686

Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

This study is a prospective, randomized controlled trial designed to evaluate the effectiveness of Miro3D Wound Matrix plus Standard of Care (SOC) compared to S…

United States30 participantsStarted 2024-11-01

Treatment: Miro3D Wound Matrix, Standard of Care (SOC)

RecruitingNot Applicable

NCT04164641

Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration…

Determining whether the utilization of Noraxon myoRESEARCH Software gait analysis Evaluation and orthotic gait Correction can reduce diabetic foot ulceration Or…

United States69 participantsStarted 2019-12-09

Treatment: Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic

RecruitingNot Applicable

NCT07046767

CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

CAMP RWE Trial: A Multicenter hybrid platform trial comparing the effects of a prospective cohort treated with a tri-layer amnion graft or a single layer amnion…

United States165 participantsStarted 2025-10-01

Treatment: IP1: BioLab Membrane Wrap Lite IP2: BioLab Tri-Membrane Wrap, IP2: BioLab Tri-Membrane Wrap

All recent trials (46 shown)

CompletedNot Applicable

NCT05170984

MAtrix Therapy for Hard-to-heal ChrOnic Wounds

CACIPLIQ20® is currently a class III CE marked medical device available in various European and non-European countries, and currently primarily used in managing…

France191 participantsStarted 2022-02-10

Treatment: CACIPLIQ20®

Not Yet RecruitingNot Applicable

NCT07449975

Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-He…

The purpose of this study is to evaluate the efficacy of two dehydrated human umbilical cord-based medical devices, also defined as Cellular, Acellular, Matrix-…

Location not specified272 participantsStarted 2026-07

Treatment: Standard of Care (SOC), Corplex P

Lower Extremity or Diabetic Foot Ulcers

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Diabetic Foot Ulcers

Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs

Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration…

CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

All recent trials (46 shown)

MAtrix Therapy for Hard-to-heal ChrOnic Wounds

Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-He…

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Diabetic Foot Ulcers

Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs

Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration…

CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

All recent trials (46 shown)

MAtrix Therapy for Hard-to-heal ChrOnic Wounds

Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-He…

Transcutaneous Application of Gaseous CO2

Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AM

A Prospective Trial of Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AC

EDX110 - Efficacy and Safety in the Management of Hard-to-heal Wounds

Short or Long Antibiotic Regimes in Orthopaedics

Blue Light Photobiomodulation Therapy on Neuroischemic Patients

LSCI and Thermography in Diabetic Foot Patients Affected by Ulcer(s): (MY-FOOT-B)

Toe Amputations in Patients With Diabetes

Efficacy and Tolerance of URGO AWC_008 and URGO AWC_022 Dressings (EXPANSION)

Use of Real-time Fluorescence Imaging in Diabetic Foot Ulcers: the Impact of Colonization

MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation

Safety Trial of the RedDress Wound Care System (RD1) in Management of Texas 1a or 2a Neuropathic Diabetic Foot Ulcers.

Larval Debridement Therapy Versus Sharp Debridement to Remove Biofilm

Efficacy and Safety of Garamycin® Sponge in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection

Non-healing Diabetic Foot Ulcers (DFU) Treated With SoC With or Without NEOX®CORD 1K

A Pilot Study to Assess the Efficacy of NEOX® CORD 1K® in the Treatment of Complex Diabetic Wounds

Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study

A Subjective Observational Study of Patients Using Medicated Footbath/Footwash Treatment in Podiatry Care