Infant Newborn Disease

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Infant Newborn Disease trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 47 trials

RecruitingPhase 2

NCT06747858

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy o…

United States33 participantsStarted 2024-12-12

Treatment: ARCT-032

RecruitingNot Applicable

NCT05612256

Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants

Electrical impedance tomography (EIT) enables assessment of regional lung ventilation at the bedside. EIT has been safely used in newborn infants to image intra…

Switzerland86 participantsStarted 2022-12-10

Treatment: Electrical impedance tomography (EIT), Forced oscillation technique (FOT)

RecruitingPhase 2

NCT07450547

Phase 2 Study to Assess the Safety and Efficacy of ANG003

In this study, ANG003, a pancreatic enzyme replacement therapy (PERT; commonly called "enzymes"), is being investigated as a potential treatment for exocrine pa…

United States113 participantsStarted 2026-04-24

Treatment: ANG003 Dose A, ANG003 Dose B

RecruitingPhase 3

NCT06449651

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

The purpose of this study is to evaluate the effectiveness of nipocalimab compared with placebo in reducing the risk of severe fetal and neonatal alloimmune thr…

Belgium, Brazil, France39 participantsStarted 2024-11-11

Treatment: Nipocalimab, Placebo

RecruitingPhase 3

NCT05912517

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

The purpose of this study is to assess the effectiveness of nipocalimab when compared to placebo in decreasing the risk of fetal anemia (a condition in which a…

United States120 participantsStarted 2023-12-20

Treatment: Nipocalimab, Placebo

RecruitingNot Applicable

NCT07194070

A Study on Hemolytic Disease of the Fetus and Newborn (HDFN) Through Global Registry

The purpose of this non-interventional study is to prospectively evaluate the risk of anemia (decreased red blood cells) in fetuses (baby before birth) and neon…

United States, Australia175 participantsStarted 2025-12-17

Treatment: Standard of Care

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07564882

The Effect of Music and Musical Mobile Interventions on Pain and Physiological Parameters

Chest tube removal in infants undergoing surgery for congenital heart disease is an invasive procedure associated with significant pain and physiological stress…

Location not specified54 participantsStarted 2026-04-30

Treatment: Music Group, Musical Mobile Group

Active — Not RecruitingNot Applicable

NCT04956354

The Use of Wireless Sensors in Neonatal Intensive Care

The study will be conducted in a convenience sample of 75 infants admitted to the NICU at the Montreal Children's Hospital, divided into 3 phases: (a) Phase 1a…

Canada75 participantsStarted 2022-08-15

Treatment: ANNE™ Monitoring System (2 sensors) - version B, ANNE™ Monitoring System (2 sensors) - version C

Infant Newborn Disease

Trial phase breakdown

Trial status

Actively recruiting — 47 trials

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants

Phase 2 Study to Assess the Safety and Efficacy of ANG003

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

A Study on Hemolytic Disease of the Fetus and Newborn (HDFN) Through Global Registry

All recent trials (100 shown)

The Effect of Music and Musical Mobile Interventions on Pain and Physiological Parameters

The Use of Wireless Sensors in Neonatal Intensive Care

Trial phase breakdown

Trial status

Actively recruiting — 47 trials

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants

Phase 2 Study to Assess the Safety and Efficacy of ANG003

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

A Study on Hemolytic Disease of the Fetus and Newborn (HDFN) Through Global Registry

All recent trials (100 shown)

The Effect of Music and Musical Mobile Interventions on Pain and Physiological Parameters

The Use of Wireless Sensors in Neonatal Intensive Care

Human Milk Concentrating Device to Optimize Mother's Own Milk

Pharmacokinetics of Omadacycline in Cystic Fibrosis

Wireless Irradiance SEnsors During Neonatal Phototherapy

Effectiveness of Simulation-based Training Delivered to Special Newborn Care Providers on Resuscitation Management and K…

Clinical Genetics Branch Eligibility Screening Survey

Tissue Doppler Echocardiographic Assessment of Cardiac Function in Neonatal Sepsis

DEUX OEUFs: Cracking the Potential of Eggs to Improve Child Growth and Development

Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia

Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Add…

Pharmacokinetics and Placental Transfer of Caffeine

Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD

Correlation of Cardiac Index Measured by the PRAM Method With NIRS and Lactate Levels in Pediatric Aortic Coarctation Su…

Feasibility and Acceptance of SonoHeal for Airway Clearance and Preliminary Comparison With the Standard of Care

A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis

Effects of Transitional Circulation in ELBW Infants

Ultrasound-Guided Long vs Short Peripheral IV Catheters in Neonates With Congenital Syphilis Receiving Antibiotics

ADX-629 Therapy for Sjogren-Larsson Syndrome

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy