Pharmacokinetics of Omadacycline in Cystic Fibrosis

Inclusion Criteria: * Diagnosis of CF based on positive sweat chloride or known CF mutation * Age \>=18 years Exclusion Criteria: * Presence of an ongoing acute pulmonary exacerbation defined based on clinical signs \& symptoms and an acute decline in relative FEV1 of 10% or greater. * Pregnancy or breastfeeding * Serious past allergy to a tetracycline antibiotic * No alcohol, nicotine, or caffeine-containing products during the study period * Hemoglobin \< 8 g/dL