G6PD Deficiency

Clinical trial pipeline · Data from ClinicalTrials.gov

See which G6PD Deficiency trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingNot Applicable

NCT07110987

The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect H…

This is a prospective, open-label, randomized controlled trial conducted at Lattakia University Hospital (Tishreen University), aiming to evaluate the efficacy…

Syria70 participantsStarted 2025-06-26

Treatment: Phototherapy, ursodeoxycholic acid (UDCA)

RecruitingPhase 3

NCT06923592

Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar

The resilience of P. vivax to malaria elimination efforts is due to its ability to form dormant liver stages (hypnozoites) that reactivate weeks to months after…

Ethiopia, Madagascar19,200 participantsStarted 2025-05-12

Treatment: PvSeroTAT, Control

RecruitingPhase 4

NCT07468513

Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases.

A non randomized observation study that is aiming to assess the safety and efficacy of high dose primaquine (1mg/kg per day over 7 days) among patients with int…

Brazil, Ethiopia, Papua New Guinea100 participantsStarted 2024-05-17

Treatment: Patients with G6PD enzyme activities between 30 and <70% of the AMM will be treated with schizontocidal treatment plus high dose primaquine 1mg/kg/day for 7 days, Patients with G6PD enzyme activities <30% of the AMM will be treated with schizontocidal treatment plus 8 weekly primaquine (0.75mg/kg dose).

All recent trials (58 shown)

CompletedNot Applicable

NCT05361486

Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru

The goal of this study is to evaluate the operational feasibility of using a new treatment algorithm for Malaria Vivax in Peru. The implementation package incl…

Peru187 participantsStarted 2023-08-28

Treatment: Tafenoquine (TQ)

CompletedNot Applicable

NCT05879224

Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia

The proportion of malaria that is the Plasmodium vivax species is increasing in Indonesia. Reducing vivax malaria will require innovative solutions to cure both…

Indonesia2,999 participantsStarted 2023-08-07

Treatment: Revised case management package

G6PD Deficiency

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect H…

Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar

Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases.

All recent trials (58 shown)

Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru

Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect H…

Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar

Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases.

All recent trials (58 shown)

Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru

Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia

Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea

Baby Detect : Genomic Newborn Screening

Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective Study

Early Check: Expanded Screening in Newborns

Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients

Primaquine Enantiomers in G6PD Deficient Human Volunteers

Screening of Coexistence Between Sickle Cell Anaemia and G6PD Deficiency

Erythrocyte and Adipocyte G6PD Activity Levels in Obesity

Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS…

A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh

Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in Thailand

Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitativ…

Oxidative Stress, Carbohydrate Metabolism Disorders and G6PD Deficiency

Evaluation of the STANDARD G6PD Rapid Test for Assaying the Enzymatic Activity of G6PD in French Guiana

Validation of Diagnostics to Identify Glucose-6-phosphate Dehydrogenase Activity in the US

G6PD Deficiency in Infarction Patients in Shaanxi Province

Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency (SAST)