The purpose of this study is to investigate the effects of alpha-lipoic acid supplementation on redox status, physiological and biochemical parameters in diabetic individuals with G6PD deficiency, after acute exercise.
Age range
18 Years – 65 Years
Sex
ALL
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Changes in total antioxidant capacity following 4 weeks of supplementation and placebo at rest and following a trial of acute exercise.
Timeframe: Before, immediately after and 1 hour after each trial of exercise, in both conditions (supplement and placebo)
Changes in glutathione following 4 weeks of supplementation and placebo at rest and following a trial of acute exercise.
Timeframe: Before, immediately after and 1 hour after each trial of exercise, in both conditions (supplement and placebo)
Changes in uric acid following 4 weeks of supplementation and placebo at rest and following a trial of acute exercise.
Timeframe: Before, immediately after and 1 hour after each trial of exercise, in both conditions (supplement and placebo)
Changes in bilirubin following 4 weeks of supplementation and placebo at rest and following a trial of acute exercise.
Timeframe: Before, immediately after and 1 hour after each trial of exercise, in both conditions (supplement and placebo)
Changes in lipid peroxidation following 4 weeks of supplementation and placebo at rest and following a trial of acute exercise.
Timeframe: Before, immediately after and 1 hour after each trial of exercise, in both conditions (supplement and placebo)
Changes in protein carbonyls following 4 weeks of supplementation and placebo at rest and following a trial of acute exercise.
Timeframe: Before, immediately after and 1 hour after each trial of exercise, in both conditions (supplement and placebo)
Changes in blood lipids following 4 weeks of supplementation and placebo at rest and following a trial of acute exercise.
Timeframe: Before, immediately after and 1 hour after each trial of exercise, in both conditions (supplement and placebo)
Changes in insulin resistance following 4 weeks of supplementation and placebo.
Timeframe: Before and following 4 weeks of supplementation and placebo.
Changes in glycated hemoglobin (HbA1c) following 4 weeks of supplementation and placebo.
Timeframe: Before and following 4 weeks of supplementation and placebo.