Bacterial Resistance

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Bacterial Resistance trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

RecruitingPhase 2

NCT02354014

Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of M…

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (explores what the body does to the drug), and anti-mycobacterial activity o…

Mozambique, Philippines, Russia60 participantsStarted 2016-05-03

Treatment: Bedaquiline (TMC207), Background Regimen (BR)

RecruitingPhase 4

NCT07314281

Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever

1. Primary Objective: o To evaluate the efficacy of intravenous azithromycin compared with meropenem in the treatment of extensively drug-resistant (XDR) en…

Pakistan40 participantsStarted 2025-04-22

Treatment: Azithromycin, Meropenem Injection

RecruitingNot Applicable

NCT01212003

Training Protocol on the Natural History of Tuberculosis

Background: \- Tuberculosis (TB) is an infectious disease that affects numerous people worldwide. Researchers are interested in actively recruiting individuals…

United States150 participantsStarted 2011-06-30

RecruitingPhase 3

NCT07209761

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

This study aims to assess quabodepistat-based treatment regimens for RR/MDR-TB. The study will enroll adults and adolescents with rifampicin-resistant or multid…

China532 participantsStarted 2025-10-16

Treatment: BPaQM, BPaLM

RecruitingPhase 2

NCT07451171

Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children

The purpose of this Phase IIa study is to identify the most effective antibiotic regimen to treat small intestine bacterial overgrowth (SIBO) in impoverished Ba…

Bangladesh60 participantsStarted 2026-04-18

Treatment: Trimethoprim-sulfamethoxazole (TMP/SMX), Metronidazole

RecruitingPhase 4

NCT05137119

Staphylococcus Aureus Network Adaptive Platform Trial

The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is an International Multi-Centered Randomised Adaptive Platform Clinical Trial to evaluate a ra…

United States, Australia8,000 participantsStarted 2022-02-16

Treatment: Cefazolin, Penicillin

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT05007795

Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant Tuberculosis

Resistance to anti-tuberculosis drugs is a continually growing problem. Multidrug-resistant tuberculosis (MDRTB) is resistance to at least rifampicin and isonia…

South Africa280 participantsStarted 2026-06-01

Treatment: Targeted sequencing using the GenoScreen Deeplex assay

CompletedNot Applicable

NCT04062344

Acquisition of Resistant Enterobacteria During Oral Drug Challenge for Betalactams in Children

Direct drug provocation testing, without prior skin or in vitro testing, is the reference standard for confirming the diagnosis of drug hypersensitivity reactio…

France50 participantsStarted 2021-03-23

Treatment: Swab

Bacterial Resistance

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of M…

Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever

Training Protocol on the Natural History of Tuberculosis

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children

Staphylococcus Aureus Network Adaptive Platform Trial

All recent trials (100 shown)

Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant Tuberculosis

Acquisition of Resistant Enterobacteria During Oral Drug Challenge for Betalactams in Children

Trial phase breakdown

Trial status

Actively recruiting — 38 trials

Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of M…

Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever

Training Protocol on the Natural History of Tuberculosis

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children

Staphylococcus Aureus Network Adaptive Platform Trial

All recent trials (100 shown)

Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant Tuberculosis

Acquisition of Resistant Enterobacteria During Oral Drug Challenge for Betalactams in Children

New Techniques for Using a Saline Wash as a Diagnostic Tool for Pneumocystis Pneumonia

Animal-Assisted Visitation Program Chlorhexidine Trial

Linezolid Dosing Strategies in Drug-Resistant TB

Scrub Typhus Antibiotic Resistance Trial

Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB

P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for…

PMT for MDRO Decolonization

Breath Test-Based Assessment of SIBO in Chronic Pancreatitis and Partial Pancreatectomy

Bacterial Gene Profiling to Predict Antibiotic Resistance During Cystic Fibrosis Pulmonary Exacerbations

Characterization of the Synergistic Antibacterial Effect of Verapamil on Bacterial Isolates From Cancer Patients

Antimicrobial Stewardship Program Implementation in Brazilian Public Hospitals (PeGASUS)

Study on the Safety and Efficacy of Polymyxin E2 Methanesulfonate for Injection in the Treatment of Hospital-Acquired Ba…

Maternal- Fetal Infection

The Effect of Adjunctive Melatonin With Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial Infections

Effect of Oral Microbiota on MDRO Decolonization

Quantifying Gram-negative Resistance to Empiric Therapy in the Intensive Care Unit

Gut Microbiome-Metabolome Profiling in H. Pylori-SIBO Comorbidity

Infectious Diseases Experts as Part of the Antibiotic Stewardship Team in Primary Care