Adverse Drug Reaction

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Adverse Drug Reaction trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 37 trials

RecruitingNot Applicable

NCT04659343

TDM for Optimized Outcome in Patients With mRCC.

The purpose of this observational study is to assess the role of plasma concentration monitoring of treatment drugs for patients with metastatic renal cell carc…

Denmark200 participantsStarted 2020-11-01

Treatment: Measurement of concentration of active metabolite in cancer treatment.

RecruitingNot Applicable

NCT00414115

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

The purpose of the study is (1) to identify and collect samples from children and adults who take drugs and have adverse drug reactions AND children and adults…

Canada7,000 participantsStarted 2005-08

RecruitingNot Applicable

NCT04249375

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

This project addresses the problem of adverse drug reactions in the three most frequently prescribed therapeutic classes of drugs in children: antibiotics, anal…

Canada150 participantsStarted 2020-02-20

RecruitingNot Applicable

NCT04330118

Origin and Function of Eosinophilic Polynuclear During DRESS Syndrome

Drug Hypersensitivity Syndrome or DRESS for "Drug Reaction with Eosinophilia and Systemic Symptoms" is a serious drug allergy which can be life-threatening for…

France80 participantsStarted 2020-07-15

RecruitingNot Applicable

NCT06907784

PRE-EMPTIVE PHARMACOGENOMICS IN ACUTE CARE SETTINGS WITH HEALTH ECONOMIC EVALUATIONS (PHOENIX TRIAL)

It is known that individuals respond differently to the same medicine with some people benefitting, some experiencing no effect and others suffering side-effect…

United Kingdom2,000 participantsStarted 2025-04-09

Treatment: Pharmacogenomic testing

RecruitingPhase 2

NCT06406114

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

Cephalosporin antibiotics are commonly used but can result in allergic reactions and anaphylaxis. There is no clear diagnostic approach for cephalosporin-allerg…

United States300 participantsStarted 2025-05-05

Treatment: Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing, Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07546357

AIManage Using an AI-driven CDS and Chatbot

The objective of this project is to define and test the GenAI-powered Clinical Decision Support (CDS) tool, AIManage, providing a broad range of incretin mimeti…

United States16 participantsStarted 2026-06-01

Treatment: AIManage

CompletedPhase 4

NCT04903353

Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole

This study aims to compare two FDA approved medications (aripiprazole and risperidone) for the treatment of behavioral dysregulation in children with autism spe…

United States30 participantsStarted 2022-02-01

Treatment: Comparison of Risperidone and Aripiprazole

Adverse Drug Reaction

Trial phase breakdown

Trial status

Actively recruiting — 37 trials

TDM for Optimized Outcome in Patients With mRCC.

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Origin and Function of Eosinophilic Polynuclear During DRESS Syndrome

PRE-EMPTIVE PHARMACOGENOMICS IN ACUTE CARE SETTINGS WITH HEALTH ECONOMIC EVALUATIONS (PHOENIX TRIAL)

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

All recent trials (100 shown)

AIManage Using an AI-driven CDS and Chatbot

Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole

Trial phase breakdown

Trial status

Actively recruiting — 37 trials

TDM for Optimized Outcome in Patients With mRCC.

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Origin and Function of Eosinophilic Polynuclear During DRESS Syndrome

PRE-EMPTIVE PHARMACOGENOMICS IN ACUTE CARE SETTINGS WITH HEALTH ECONOMIC EVALUATIONS (PHOENIX TRIAL)

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

All recent trials (100 shown)

AIManage Using an AI-driven CDS and Chatbot

Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole

Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental Disabilities

Population Health Approach to Optimizing Medications in Older Adults

Effectiveness of an ADE-related Hospitalization Risk Prediction Tool for Patients (ADE-RED)

Comparative Study of Different Doses of Magnesium as a Protective Agent in Nephrotoxicity in Cancer Patients

Linezolid Tolerance During the BPaL Regimen With Dosage Personalization Based on Therapeutic Drug Monitoring (TDM) Durin…

Isoniazid-Related Hepatotoxicity in Clinical Practice: Incidence and Predictors

The INTEGRATE Study: Integrated Pharmacogenetics, TDM and Active Pharmacovigilance as Innovative Tools for the Optimisat…

Effect of Remimazolam on Postoperative Delirium

MEOP - Multidimensional Evaluations in Oncological Psychiatry

Impact of Medication Education on Adherence and Side Effects

Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis

The Efficacy and Adverse Reactions of Neotetracycline in the Treatment of GNB Infections

DETECT-IP: a Clinical Decision Support System and Intelligent Procedures to Counter Some Adverse Drug Events in Older Ho…

A Study of GC101 TIL in Advanced Melanoma (BZ)

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase

Safety of Ibuprofen After Major Orthopaedic Surgeries

NATIENS: Optimal Management and Mechanisms of SJS/TEN

Evaluation of Postoperative Pain in Cases Undergoing Cataract Surgery Under Topical Versus General Anesthesia