The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's Dis… (NCT07572903) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Efficacy and Safety of Temporal Interference Stimulation on Motor Symptoms of Parkinson's Disease
China90 participantsStarted 2026-05-06
Plain-language summary
This study aimed to observe the clinical efficacy and safety of single-target transcranial temporal stimulation (tTIS) intervention in Parkinson's disease (PD) patients and explore the neurophysiological mechanism of TIS intervention. The study was designed as a three-arm (A: GPi group, B: STN group, C: Sham group), randomized, double-blind, parallel-controlled trial. PD patients in the drug-off state (≥12 hours after drug withdrawal) were randomly assigned to receive either tTIS or sham stimulation targeting GPi/STN, with each stimulation lasting 30 minutes. Clinical symptom assessments were conducted before and after the intervention, and safety was monitored by researchers throughout the process.
Who can participate
Age range40 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Age \>= 40 years;
✓. Meet the diagnostic criteria for primary Parkinson's disease (MDS Parkinson's Disease Diagnostic Criteria (2015 Edition));
✓. No medication adjustment in the 4 weeks before and during each stimulation;