RecruitingNot Applicable

Health-Related Quality of Life and Metabolic Outcomes in PCOS

United States40 participantsStarted 2026-05-23

Plain-language summary

The primary outcome of interest is change in PCOS health-related quality of life, while the secondary outcome of interest is change in adiposity, cardiometabolic, and inflammation biomarkers.

Who can participate

Age range18 Years – 49 Years

SexFEMALE

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Inclusion criteria

✓. Non-pregnant females ages 18-49 years
✓. Preexisting diagnoses of PCOS and obesity (body-mass index (BMI) equal or greater to 30 kg/m2) at enrollment

Exclusion criteria

✕. Patients who are pregnant or planning to become pregnant during the study period
✕. Patients currently or with recent participation (\< 12 months at the time of enrollment) in a PCOS-focused group
✕. Patients with documented monogenic obesity
✕. Patients with a diagnosis of any type of diabetes (with the exclusion of prediabetes)
✕. Patients on systemic glucocorticoid therapy \> 7 days at the time of enrollment
✕. Patients with any end-stage organ disease
✕. Patients without access to internet
✕. Patients requiring English language interpretation

What they're measuring

Difference in Modified PCOS Health-related Quality of life questionnaire (mPCOSQ) scoring between participants.

Timeframe: 4 months

Trial details

NCT IDNCT07571915

SponsorThe Cleveland Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-05-01

Contact for this trial

Andrea Parianos

216-445-8354 debsa@ccf.org

View on ClinicalTrials.gov More PCOS (Polycystic Ovary Syndrome) trials