Upper Punctal Plug Occlusion in Previous Lower Punctal Occlusion.
Mexico36 participantsStarted 2026-02-12
Plain-language summary
This study evaluates the therapeutic effect of upper punctal plug occlusion in patients with dry eye disease with previous lower punctal occlusion.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Patients of both sexes
* One or both eyes may be included
* Inferior lacrimal punctum occluded (with a punctal plug or cauterization), clinically sealed under slit-lamp examination
* Functional superior lacrimal punctum
* Aqueous-deficient dry eye (such as Sjögren's disease, graft-versus-host disease, or primary dry eye disease.)
* Age \>18 years
* OSDI score \>13 and one of the following signs: Tear film markers (Fluorescein tear break up-time \<5, First non-invasive tear breakup time \<10, Schirmer test without anesthesia \<10 mm, Schirmer test with anesthesia \<10 mm), Ocular surface markers (corneal staining \>5 spots or conjunctival staining \>9 spots).
Exclusion Criteria:
* Active ocular surface infection.
* Patients who are unwilling to participate or to provide written informed consent.