Comparison of Artificial Intelligence and Clinicians With Different Experience Levels in Assessin… (NCT07570290) | Clinical Trial Compass
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Comparison of Artificial Intelligence and Clinicians With Different Experience Levels in Assessing Gingival Phenotype
40 participantsStarted 2026-05-15
Plain-language summary
The goal of this observational study is to compare the performance of clinicians with different experience levels and a deep learning-based artificial intelligence (AI) model in assessing gingival phenotype using two diagnostic methods: the periodontal probe transparency method and visual assessment from standardized clinical photographs. The main questions the study aims to answer are:
Can AI achieve comparable accuracy to human examiners in both probe transparency and visual assessment methods?
Does examiner experience level influence diagnostic performance and agreement with the reference standard in these methods?
Researchers will compare AI, dental students, and periodontology research assistants to determine accuracy, sensitivity, specificity, and agreement with the gold standard for each method.
Participants will:
Undergo standardized intraoral photography of maxillary anterior teeth, with and without a periodontal probe in place, following a validated protocol.
Have gingival phenotype determined by a reference periodontologist using the probe transparency method as the gold standard.
Have their photographs evaluated by AI, dental students, and research assistants for phenotype classification using both methods.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria for Volunteer Participants Who Will Participate in Transparency and Visual Assessment:
* Systemically and periodontally healthy individuals.
* Presence of natural maxillary anterior incisors.
Exclusion Criteria:
* Presence of fixed crowns or cervical restorations on the evaluated teeth.
* Pregnant or breastfeeding women.
* Signs of gingival inflammation or periodontal disease with attachment loss.
* Presence of buccal gingival recession.
* Use of medications known to cause gingival enlargement.
* Presence of congenital anomalies or dental structural defects.
Inclusion Criteria for Clinicians:
* Research assistants: Must be currently working in the Department of Periodontology.
* Dental Intern Students: Fourth- or fifth-year students who have completed periodontology clinical rotation.
Exclusion Criteria for Clinicians:
* Those who are confirmed to be color blind by the Ishihara test
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Diagnostic Accuracy of Each Examiner Group and AI Model in the Periodontal Probe Transparency Method
Timeframe: At the time of image evaluation (single session).