LEXURE for Post-Stroke Aphasia: A Randomized, Evaluator-Blinded, Confirmatory Trial (NCT07570264) | Clinical Trial Compass
RecruitingNot Applicable
LEXURE for Post-Stroke Aphasia: A Randomized, Evaluator-Blinded, Confirmatory Trial
South Korea116 participantsStarted 2026-04-16
Plain-language summary
This study evaluates the efficacy of digital language rehabilitation using LEXURE for the treatment of post-stroke aphasia. Half of participants will receive structured language training using the LEXURE application, while the other half will receive workbook-based language training as an active comparator.
Who can participate
Age range19 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Diagnosed with hemorrhagic or ischemic stroke
✓. At least 3 months have elapsed since stroke onset
✓. History of aphasia resulting from stroke
✓. Aphasia Quotient (AQ) score between 26 and 90 (inclusive) on the Korean version of the Western Aphasia Battery (K-WAB) or the Paradise Korean version of the Western Aphasia Battery-Revised (PK-WAB-R)
✓. Adults aged 19 years or older
✓. Native Korean speakers
✓. Able to use the investigational device or perform workbook-based training without difficulty
✓. Willing to participate voluntarily and provide written informed consent
Exclusion criteria
✕. Diagnosed with language impairment due to causes other than stroke (e.g., traumatic brain injury, brain tumor, or neurodegenerative disease)
✕. History of language impairment due to developmental disorders
✕. Currently receiving speech-language therapy or participating in another clinical trial related to language function
✕. Currently receiving medication for severe psychiatric disorders (e.g., bipolar disorder, major depressive disorder, schizophrenia, alcohol dependence, or substance abuse)