Utilization of Flotufolastat 18F PET for Post-Focal Therapy Prostate Cancer Evaluation (NCT07568756) | Clinical Trial Compass
Not Yet RecruitingPhase 2
Utilization of Flotufolastat 18F PET for Post-Focal Therapy Prostate Cancer Evaluation
United States60 participantsStarted 2026-05
Plain-language summary
This is a phase II single arm, open-label clinical trial determining diagnostic accuracy of Flotufolastat F18 PET in subjects with prostate adenocarcinoma. These are subjects who have not previously received treatment for prostate cancer.
Who can participate
Age range
18 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 years or greater at time of consent
* Prostate adenocarcinoma (no other histologic subtypes allowed)
* Prostate Cancer planned to be treated by focal therapy (e.g. cryotherapy, HIFU, or NanoKnife)
* Multiparametric-MRI imaging planned
* Planned pre- and post- treatment MRI-fusion biopsy
Exclusion Criteria:
* Prior treatment for any prostate malignancy (e.g. radiation, focal therapy, or systemic therapy)
* Genomic classifiers (e.g. Decipher) signifying intermediate or high-risk disease
* PSA \>10
* High-risk prostate cancer (diagnosed by biopsy)
* Bilateral prostatic lobe disease
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Flotufolastat F18 PET findings
Timeframe: 5 years
Trial details
NCT IDNCT07568756
SponsorUniversity of California, Irvine
Sponsor typeOTHER
Study typeINTERVENTIONAL
Primary completion2028-05
Contact for this trial
Chao Family Comprehensive Cancer Center University of California, Irvine