Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circ… (NCT07567976) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age
90 participantsStarted 2026-06-01
Plain-language summary
This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control group. The primary outcome is balance function measured by the Berg Balance Scale. Secondary outcomes include physical function, psychological well-being, cognitive function, and sleep quality. The study also explores the predictive and modifying roles of baseline circadian age on intervention outcomes.
Who can participate
Age range
55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 55 years or older
* Community-dwelling
* Able to walk independently (assistive devices such as canes are permitted)
* Berg Balance Scale (BBS) score ≤52 at screening
* Able to understand and follow verbal instructions
* Willing to wear a wrist accelerometer continuously for 7 days at baseline
* Willing to accept random group assignment
* Willing to undergo blood collection during the study
* Provides written informed consent
Exclusion Criteria:
* Regular Tai Chi or yoga practice (more than once per week) within the past 6 months
* Severe cognitive impairment (Montreal Cognitive Assessment \[MoCA\] score \<20 at screening, or previously diagnosed dementia)
* Unstable cardiovascular disease (myocardial infarction, stroke, or hospitalization within the past 3 months)
* Severe musculoskeletal disease that limits exercise participation
* Neurological diseases affecting balance (e.g., Parkinson's disease, severe peripheral neuropathy)
* Currently participating in another exercise intervention study
* Planned surgery or extended absence during the study period
* Contraindications to functional near-infrared spectroscopy (fNIRS) examination (e.g., scalp injury, metallic implants in the head region)
* Severe psychiatric illness (e.g., schizophrenia, bipolar disorder)
* Considered unable to safely participate in moderate-intensity physical activity as judged by the study physician or attending healthcare provider
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Berg Balance Scale (BBS) Score
Timeframe: Change from baseline to end of intervention, up to 12 weeks