Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circ… (NCT07567976) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age
90 participantsStarted 2026-05-15
Plain-language summary
This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control group. The primary outcome is balance function measured by the Berg Balance Scale. Secondary outcomes include physical function, cognitive function, psychological well-being, and sleep quality. The study also explores the predictive and modifying roles of circadian age on intervention outcomes.
Who can participate
Age range55 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 55 years or older
* Community-dwelling
* Able to walk independently (assistive devices such as canes are permitted)
* Berg Balance Scale (BBS) score ≤52 at screening
* Able to understand and follow verbal instructions
* Willing to wear a wrist accelerometer continuously for 7 days at baseline
* Willing to accept random group assignment
* Willing to undergo blood collection during the study
* Provides written informed consent
Exclusion Criteria:
* Regular Tai Chi or yoga practice (more than once per week) within the past 6 months
* Severe cognitive impairment (Montreal Cognitive Assessment \[MoCA\] score \<20 at screening, or previously diagnosed dementia)
* Unstable cardiovascular disease (myocardial infarction, stroke, or hospitalization within the past 3 months)
* Severe musculoskeletal disease that limits exercise participation
* Neurological diseases affecting balance (e.g., Parkinson's disease, severe peripheral neuropathy)
* Currently participating in another exercise intervention study
* Planned surgery or extended absence during the study period
* Contraindications to functional near-infrared spectroscopy (fNIRS) examination (e.g., scalp injury, metallic implants in the head region)
* Severe psychiatric illness (e.g., schizophrenia, bipolar disorder)
* Considered unable to safely participate in moderate-intensity physical activity as judged by the study physician or attending healthcare provider
What they're measuring
1
Change in Berg Balance Scale (BBS) Score
Timeframe: Change from baseline to end of intervention, up to 12 weeks