Non-Invasive Vagus Nerve Stimulation in Burn Patients During Dressing (NCT07566910) | Clinical Trial Compass
By InvitationNot Applicable
Non-Invasive Vagus Nerve Stimulation in Burn Patients During Dressing
Turkey (Türkiye)96 participantsStarted 2026-05
Plain-language summary
This study will evaluate the effects of non-invasive vagus nerve stimulation on pain, anxiety, and quality of life in burn patients during the dressing process. Participants will be randomly assigned to one of three groups. One group will receive non-invasive vagus nerve stimulation for 20 minutes before dressing, one group will receive non-invasive vagus nerve stimulation for 20 minutes during dressing, and the control group will receive standard dressing care only. Pain will be assessed using the Visual Analog Scale, anxiety will be assessed using the Beck Anxiety Inventory, and quality of life will be assessed using the SF-12 Health Survey. The study aims to determine whether non-invasive vagus nerve stimulation can reduce dressing-related pain and anxiety and improve quality of life in burn patients.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18 to 65 years
* Having superficial or deep second-degree burns requiring dressing during the acute period
* Expected to attend at least 7 dressing sessions
* Willing to participate in the study and able to provide written informed consent
* Able to read and understand Turkish
Exclusion Criteria:
* Infection, ulcer, or scar tissue on the auricle
* Burns in the head and neck region that prevent application of the device to the auricular vagus nerve area
* Metallic implant in the skull
* Excessive sensitivity, injury, or inflammation in the ear
* Chronic pulmonary and/or cardiac disease
* Heart rate below 60 beats per minute
* Presence of a pacemaker or cochlear implant
* Uncontrolled hypertension
* Lack of cooperation
* Refusal or inability to sign the informed consent form
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Pain Intensity
Timeframe: Before and after each dressing session through 7 dressing sessions, approximately 14 days
2
Change in Anxiety Level
Timeframe: Before the first dressing session and before the seventh dressing session, approximately 14 days
3
Change in Quality of Life
Timeframe: Before the first dressing session and before the seventh dressing session, approximately 14 days