Prevalence of Sarcopenia and Its Associated Factors in Patients With Knee Osteoarthritis in a Ter… (NCT07566520) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Prevalence of Sarcopenia and Its Associated Factors in Patients With Knee Osteoarthritis in a Tertiary Care Hospital in Upper Egypt
Egypt224 participantsStarted 2026-05
Plain-language summary
Osteoarthritis (OA) and sarcopenia are two highly prevalent, interconnected geriatric syndromes that often coexist, leading to a condition termed "osteosarcopenia". Globally, the pooled prevalence of sarcopenia in patients with knee OA is estimated at approximately 25.07%, significantly higher than in the general population.
Who can participate
Age range40 Years
SexALL
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Inclusion Criteria:
* Adults aged 40 years and older diagnosed with knee OA based on the American College of Rheumatology (ACR) criteria.
* Patients who are willing to participate and provide informed written consent.Exclusion Criteria:
* Inflammatory arthritis: patients with rheumatoid arthritis, gouty arthritis, or systemic lupus erythematosus (SLE) to avoid confusion with inflammatory muscle wasting.
* Physical Limitations: amputees or those with severe physical deformities preventing gait speed tests or handgrip measurement.
* Patients with cardiac pacemakers or implanted electronic devices (as these interfere with Bioelectrical Impedance Analysis (BIA)).
* Severe Comorbidities: end-stage renal or hepatic disease, advanced malignancy or cachexia.
* Severe neurological disorders (e.g., Parkinson's disease, Stroke with paralysis) that directly affect muscle mass and mobility.
* Prolonged use of systemic corticosteroids (which cause secondary sarcopenia)
What they're measuring
1
Prevalence of sarcopenia in knee osteoarthritis patients