MBA Early Feasibility Study

Inclusion criteria

• . Thoracic pathologies with involvement of the arch branch vessels, that are compatible with the treatment requirements of the MBA device, and meeting any of the following criteria:
• . Anatomic compatibility with MBA device and other devices required for proximal or distal extensions based on Gore's review.
• . Adequate vascular access via transfemoral or retroperitoneal approach.
• . Appropriate vascular access to allow for through-wire access to the brachiocephalic artery, LCCA, and LSA.
• . Proximal Aortic Landing Zone:
• . Proximal segment length (length from distal edge of brachiocephalic artery to distal edge of the most distal coronary artery) must be ≥ 2 cm longer than the "AC Proximal End to BCA Portal Length" for the selected Aortic Component or ≥ 3 cm if the landing zone is \> 42 mm.
• . For patients with patent bypass graft from the ascending aorta, proximal extent of landing zone must be ≥ 1 cm distal to the bypass graft.
• . For patients with prior replacement of the ascending aorta and / or aortic arch by surgical graft, there must be ≥ 2 cm overlap of MBA device and previously implanted graft.

Exclusion criteria