Effect of Neurodynamic Mobilization of Vagus Nerve on Irritable Bowel Syndrome in Women

Inclusion Criteria: * 32 Females with mild to moderate IBS ,were recruited for this study by referral from a physician. * aged 20-45 (i.e., the most common age for developing IBS) * Patients must experience abdominal pain recurring at least once weekly over the past three months. * This pain must be linked to two or more of the following features: occurring in relation to defecation, accompanied by a change in stool frequency, or accompanied by a change in stool form or appearance. * Symptoms should have been present during the last three months, with onset at least six months before diagnosis. Exclusion Criteria: Subjects will be excluded if they have: * Organic gastrointestinal disorders. * Thyroid abnormalities. * Coexisting cardiovascular, respiratory, renal, or hepatic conditions. * Pregnancy. * Blood disorders. (e.g., hemophilia, coagulation disorders, leukemia, thalassemia, sickle cell disease). * Neurological or musculoskeletal conditions affecting muscle tone. * Psychiatric illnesses ( patients with depression in the absence of IBS). * Fibromyalgia. * A history of gastrointestinal surgery or resection, , or other chronic diseases associated with gastrointestinal issues such as inflammatory bowel disease, ulcers, or cancer. * A history of alcohol or drug abuse, abdominal surgery within the past six months. * Recent cervical or cardiac surgery, or recent major trauma.