PROMET-BR is an observational, retrospective and prospective real-world study in Brazil designed to characterize clinically relevant molecular alterations in metastatic prostate cancer and explore their association with patient outcomes in routine practice. The study will be conducted within OncoclĂnicas \& Co and will integrate centralized biomarker testing performed at OC Precision Medicine laboratories with retrospectively assembled clinical data from electronic health records (EHRs) from participating sites. Treatments are not assigned by the protocol; patients receive standard-of-care palliative systemic therapy at the discretion of their treating physicians.
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prevalence of HRR mutations in tissue and/or liquid biopsy samples
Timeframe: april 2026 to april 2027
prevalence of PTEN loss of expression in tissue samples
Timeframe: april 2026 to april 2027