This is a prospective, observational cohort study involving 40 patients with primary knee osteoarthritis hospitalized in a rehabilitation hospital in Cluj-Napoca. All participants will receive intra-articular platelet-rich plasma (PRP) injections. The study aims to analyze PRP composition and inflammatory biomarkers to better understand disease mechanisms and evaluate treatment effectiveness.
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Pain intensity
Timeframe: Baseline and at 4 weeks
Functional status and symptom severity
Timeframe: Basline and at 4 weeks
Systemic inflammatory markers
Timeframe: Baseline and at 4 weeks
General inflammatory indicators
Timeframe: Baseline and at 4 weeks
General inflammatory indicators 2
Timeframe: Baseline and at 4 weeks
Growth factor profile of PRP
Timeframe: Baseline