A Multimodal Prospective Cohort Study of Parkinsonism

Inclusion Criteria: For participants with rapid eye movement sleep behavior disorder: * Meets the diagnostic criteria for rapid eye movement sleep behavior disorder established by the American Academy of Sleep Medicine * Chinese citizen * Age \>30 years and \<80 years * Able to understand the study, show good compliance, and provide written informed consent personally or through a legal representative For participants with Parkinsonism: * Meets the diagnostic criteria for Parkinsonism established by the International Parkinson and Movement Disorder Society * Chinese citizen * Age \>30 years and \<80 years * Able to understand the study, show good compliance, and provide written informed consent personally or through a legal representative For healthy controls: * No neurodegenerative disease, no history of head trauma or head surgery, no history of stroke, epilepsy, tumor, or psychiatric disease * No metal implants or cardiac pacemaker * No severe chronic disease or severe hepatic or renal insufficiency * Chinese citizen * Age \>30 years and \<80 years * Education level of primary school or above * Able to understand the study, show good compliance, and provide written informed consent personally or through a legal representative Exclusion Criteria: * Significant cognitive impairment (MMSE ≤23) * Unable to sign the informed consent form or unable to complete study procedures for other reasons * Any other condition that, in the opinion of the investigator, makes the par…