Safety, PK, and PD of BSA204 in Chinese Adults With Borderline Elevated Lipoprotein(a)

Inclusion Criteria: * Body mass index (BMI) 18 to 30 kg/m2 * Fasting triglycerides (TG) ≤ 4.5 mmol/L * Borderline elevated fasting lipoprotein(a) \[Lp(a)\] levels as defined in the protocol * Fasting low-density lipoprotein cholesterol (LDL-C) within the range specified for the assigned dose cohort * o clinically significant abnormalities of hepatic or renal function Exclusion Criteria: * Pregnant or lactating women. * History or presence of significant medical conditions * Abnormal ECG findings, including a prolonged QTcF interval (\> 450 msec for males or \> 470 msec for females) * Prior treatment with small interfering RNA (siRNA) or antisense oligonucleotides within 12 months, or recent use of specific lipid-lowering therapies * Known allergy to any component of the study drug