Hemodynamic Effects of Lithotomy Position in Surgical Patients (PH-LITHO) (NCT07549152) | Clinical Trial Compass
CompletedNot Applicable
Hemodynamic Effects of Lithotomy Position in Surgical Patients (PH-LITHO)
Turkey (Türkiye)60 participantsStarted 2021-03-01
Plain-language summary
Anesthesia-induced hypotension is a common occurrence in elderly hypertensive patients and is closely associated with increased postoperative morbidity
* This study aims to investigate whether the lithotomy position, a non-pharmacological and cost-free approach, can reduce the incidence of post-induction hypotension (PIH) in this high-risk population by increasing venous return
Sixty patients aged 65-80 with a history of hypertension were randomly assigned to either the Supine Group (Group S) or the Lithotomy Group (Group L)
* In Group L, patients were placed in the lithotomy position 120 seconds before the start of anesthesia induction
* Blood pressure was monitored every minute for the first five minutes following induction
* The study evaluates whether this simple positioning strategy can maintain hemodynamic stability, reduce the drop in mean arterial pressure, and decrease the overall need for vasopressor medications like ephedrine
Who can participate
Age range
65 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged between 65 and 80 years.
* American Society of Anesthesiologists (ASA) physical status class II or III.
* Clinical diagnosis of hypertension.
* Continuous use of the same antihypertensive medication for at least 6 months.
* Scheduled for elective surgery requiring the lithotomy position.
Exclusion Criteria:
* Uncontrolled hypertension.
* Arrhythmias requiring medical treatment.
* Left ventricular ejection fraction (LVEF) \< 40%.
* Unstable ischemic heart disease.
* Physical inability to be placed in the lithotomy position.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of Post-induction Hypotension (PIH)
Timeframe: Within the first 5 minutes following the completion of anesthesia induction (measurements recorded at minutes 0, 1, 2, 3, 4, and 5)