CompletedNot Applicable

Effect of Probiotic Supplementation on Gingival Health in Orthodontic Patients

Poland100 participantsStarted 2021-12-01

Plain-language summary

This study evaluated the effect of probiotic supplementation on gingival health in orthodontic patients. Participants undergoing fixed orthodontic treatment were randomly assigned to receive either a probiotic preparation containing Limosilactobacillus reuteri or no The primary objective was to assess changes in gingival inflammation using clinical periodontal indices(BOP). Secondary outcomes included plaque accumulation(PI) . The results of this study may help determine whether probiotic supplementation can support gingival health during orthodontic treatment

Who can participate

Age range18 Years – 59 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Generally healthy patient * Age 18-59 years * Fixed-appliance orthodontic treatment * Plaque-induced gingivitis (BOP \> 10%, PD ≤ 4 mm) Exclusion Criteria: * Hypersensitivity to product components * Smoking * Use of any probiotics within the past 30 days * Antibiotic or other antimicrobial therapy within the past month * Use of antibacterial chlorhexidine rinses within the past 2 weeks * Age \< 18 or \> 59 years.

What they're measuring

Change in gingival inflammation.

Timeframe: from baseline to 12 weeks

Trial details

NCT IDNCT07548138

SponsorMedical University of Warsaw

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-10

View on ClinicalTrials.gov More Gingivitis trials