Evaluation of the Efficacy and Safety of Palmitoleic Acid Oil Composition in Preventing Pressure Injuries

Inclusion Criteria: * Adult inpatients (aged above 18 years). * High risk for sacral pressure injuries, objectively defined by an abnormal hydration status (Sacral Subepidermal Moisture \[SEM\] Delta \> 0.5) at screening. Exclusion Criteria: * Medical contraindications to standard repositioning protocols (e.g., unstable pelvic fractures). * Use of topical medications or advanced prophylactic dressings on the sacrum within 14 days prior to enrollment. * Active peripheral vascular disease significantly impairing local tissue perfusion. * Documented hypersensitivity to the investigational product (POA) or its vehicle components.