Choroidal Response to the Modified Defocus Incorporated Multiple Segments Spectacle Lenses

Inclusion Criteria: * Hong Kong Chinese * Age at enrolment: 6 - 13 years * Myopia in spherical power: -1.00D to -5.00D in both eyes * Astigmatism: equal or less than 2.00D * The sum of spherical power and astigmatism: equal or less than -7.00D * Anisometropia (spherical equivalent refraction (SER)): equal or less than 1.50D * Previous myopia progression (valid documentation dated within 2 years before screening): * -0.50D (SER) per year or more in both eyes OR Axial length elongation: 0.27mm/year in both eyes * If myopia is initially detected during screening, eligibility requires myopia (in SER) below the 3rd percentile curve of refraction in both eyes.12 * Best corrected visual acuity: LogMAR 0.04 or better in both eyes * Ocular health: no abnormalities in both internal and external ocular health * Binocular vision: no strabismus and other binocular abnormalities * Normal colour vision * Willing to wear the study spectacles all the time (10 hours per day, for 7 days per week) Exclusion Criteria: * Previous or current treatment for myopia control (e.g., red-light therapy, atropine, orthokeratology, specialized spectacle lenses and contact lenses and oral supplements for myopic control) * Existing or past eye diseases or surgeries (e.g., strabismus surgery, amblyopia, oculomotor nerve palsies, corneal disease, intraocular disease, etc.) that may have an impact on vision or visual development * Long-term medication (intake at least 3 days/week) or medication/supplement…