This study shows that in craniotomy patients using a skull pin head holder, an ultrasound-guided scalp block reduces perioperative opioid consumption, improves hemodynamic stability, and decreases the inflammatory response.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18 years and older
* Scheduled for elective intracranial surgery with skull pin head holder fixation
* Classified as American Society of Anesthesiologists (ASA) physical status I-III
* Provided written informed consent in the preoperative period
Exclusion Criteria:
* Allergy to local anesthetics
* Coagulopathy or anticoagulant use
* Local infection at injection site
* Pregnancy or breastfeeding
* Chronic opioid use (\>3 months) or chronic pain syndrome
* Severe psychiatric disorders affecting pain assessment
* Emergency surgery
* Active infection or rheumatic disease
* Hematological disease or malignancy (active or within 5 years)
* Recent use of biological agents, chemotherapy, or corticosteroids (within 30 days)
* NSAID use within 24 hours before surgery
* Advanced organ failure (NYHA III-IV, Child-Pugh C, eGFR \<30 mL/min)
* Refusal to participate
* Communication difficulties preventing pain assessment
What they're measuring
1
Total opioid consumption within 24 hours postoperatively (morphine milligram equivalents, mg)
Timeframe: 0-24 hours postoperatively
Trial details
NCT IDNCT07545655
SponsorFatih Sultan Mehmet Training and Research Hospital