Effects of Ultrasound-Guided Scalp Block on Opioid Use, Hemodynamics, and Postoperative Inflammat… (NCT07545655) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Effects of Ultrasound-Guided Scalp Block on Opioid Use, Hemodynamics, and Postoperative Inflammation in Craniotomy
Turkey (Türkiye)60 participantsStarted 2026-04-10
Plain-language summary
This study shows that in craniotomy patients using a skull pin head holder, an ultrasound-guided scalp block reduces perioperative opioid consumption, improves hemodynamic stability, and decreases the inflammatory response.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18 years and older
* Scheduled for elective intracranial surgery with skull pin head holder fixation
* Classified as American Society of Anesthesiologists (ASA) physical status I-III
* Provided written informed consent in the preoperative period
Exclusion Criteria:
* Allergy to local anesthetics
* Coagulopathy or anticoagulant use
* Local infection at injection site
* Pregnancy or breastfeeding
* Chronic opioid use (\>3 months) or chronic pain syndrome
* Severe psychiatric disorders affecting pain assessment
* Emergency surgery
* Active infection or rheumatic disease
* Hematological disease or malignancy (active or within 5 years)
* Recent use of biological agents, chemotherapy, or corticosteroids (within 30 days)
* NSAID use within 24 hours before surgery
* Advanced organ failure (NYHA III-IV, Child-Pugh C, eGFR \<30 mL/min)
* Refusal to participate
* Communication difficulties preventing pain assessment
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Total opioid consumption within 24 hours postoperatively (morphine milligram equivalents, mg)
Timeframe: 0-24 hours postoperatively
Trial details
NCT IDNCT07545655
SponsorFatih Sultan Mehmet Training and Research Hospital