Robotic-Assisted Bronchoscopy-Guided Synchronous Biopsy and Radiofrequency Ablation for Pulmonary… (NCT07545057) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Robotic-Assisted Bronchoscopy-Guided Synchronous Biopsy and Radiofrequency Ablation for Pulmonary Nodules
China76 participantsStarted 2026-05-01
Plain-language summary
This is a prospective, single-arm, open-label clinical study. The primary study objective is to evaluate the feasibility of synchronous biopsy and radiofrequency ablation for pulmonary nodules under robotic-assisted bronchoscopy.
Who can participate
Age range18 Years – 100 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 18 years old;
* Chest CT indicates pulmonary nodules, highly suspected of being malignant;
* Size of pulmonary nodules: 8 mm \< maximum diameter ≤ 30 mm, and the number of pulmonary nodules requiring intervention ≤ 3;
* Preoperative imaging evaluation indicates no clear lymph node metastasis or distant metastasis (cT1N0M0);
* Multidisciplinary evaluation shows that the patient cannot tolerate surgery and radiotherapy, or the patient refuses surgery and radiotherapy after full informed consent;
* The patient understands and agrees to receive synchronous biopsy and ablation treatment under robotic-assisted bronchoscopy and signs a written informed consent form.
Exclusion Criteria:
* Patients who cannot tolerate general anesthesia due to advanced age or severe cardiopulmonary diseases, or other reasons;
* The target nodule has been diagnosed as a malignant tumor or metastasis;
* Patients with severe bleeding tendency or uncorrectable coagulation disorder (platelet count \< 50×10\^9 /L, prothrombin time \> 18s, prothrombin activity \< 40%);
* Severe pulmonary fibrosis and pulmonary hypertension;
* Anticoagulant or anti-platelet drugs have not been discontinued for the required time before surgery;
* Implanted cardiac pacemaker, defibrillator, or other electronic implants;
* Presence of important blood vessels that cannot be avoided along the biopsy path;
* Other conditions that the investigators consider not suitable for the patient to participate i…