Early Partial Weight-bearing May Improve Functional Recovery Without Increasing Complications Des… (NCT07538726) | Clinical Trial Compass
RecruitingNot Applicable
Early Partial Weight-bearing May Improve Functional Recovery Without Increasing Complications Despite This Potential, Limited Randomized Studies Have Evaluated Early Weight-bearing After Pelvic Fixation Surgeries
Egypt50 participantsStarted 2025-08-31
Plain-language summary
The goal of this randomized clinical trial is to compare between the effect of immediate weight bearing (WB) versus delayed weight bearing in improving function, pain, gait, quality of reduction radiologically, muscle strength, and quality of life outcomes in individuals who underwent specific pelvic fixation surgeries.
Who can participate
Age range18 Years – 55 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 18 to 55 years
* Traumatic fractures indicated for pelvic fixation.
* All Types B after stable anterior and / or posterior fixation.
* Type C, Stable fixation:
Posterior fixation by triangular osteosynthesis. oTrans-iliac trans-sacral screw fixation or Trans iliac plate or posterior infex combined with anterior fixation.
• Excellent to good quality of fracture reduction by Matta and Tornetta radiological assessment.
Exclusion Criteria:
* Associated lower extremity fractures that independently restrict or contraindicate weight-bearing activities.
* Bilateral unstable after fixation pelvic ring disruption.
* Patients with associated spinal cord injury, as neurological deficits may alter gait, functional recovery, and weight-bearing capacity, thereby affecting the validity and generalizability of the outcome measures.
* Current history of acute systemic infection, active Bone inflammatory disease, (e.g., osteomyelitis, chronic non-bacterial osteitis), or malignancy, which may compromise the healing process, confound clinical outcomes, or pose additional medical risks during rehabilitation.
* Uncontrolled Diabetes
* Cancer
* Active infection
* Morbid obesity (BMI \> 40)
* Alcohol use disorder (AUD). Alcohol abuse as defined by the National Institute on Alcohol Abuse and Alcoholism: "Drinking at Low Risk for Developing Alcohol Use Disorder: For women, low-risk drinking is defined as no more than 3 drinks on any single day and no more than 7 drinks …