Not Yet RecruitingPhase 4

Evaluation of Pain Treatment After Total Knee Arthroplasty

60 participantsStarted 2026-04-22

Plain-language summary

The purpose of the study is to characterize opioid use after total knee arthroplasty (TKA).

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Key Inclusion Criteria: * Body mass index (BMI) of greater than or equal to (≥) 18.0 to less than or equal to (≤) 40.0 kilogram per meter square (kg/m\^2) * Scheduled to undergo an elective primary unilateral TKA surgery Key Exclusion Criteria: \- History of previous TKA surgery on incident side Other protocol defined Inclusion/Exclusion criteria will apply.

What they're measuring

Proportion of Participants who Remain Opioid-Free

Timeframe: From Day 1 up to Day 14

Trial details

NCT IDNCT07538570

SponsorVertex Pharmaceuticals Incorporated

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2027-01-30

Contact for this trial

Medical Information

617-341-6777 medicalinfo@vrtx.com

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