The goal of this observational study is to understand how diet may influence the disease characteristics of inclusion body myositis (IBM). Research findings will help determine whether dietary factors could play a role in managing IBM. The study aims to answer the question: Does diet affect the muscle health and functional ability of people living with IBM? Researchers will compare adults with IBM to healthy volunteers aged 40 years and older. This comparison will help to identify which findings are related to normal ageing and which are specific to IBM. Participants will: Attend an initial screening visit at the Manchester Metropolitan University Institute of Sport to confirm eligibility and explain study procedures. Complete four weeks of home-based monitoring, including dietary records, physical activity monitoring, and questionnaires about lifestyle and symptoms. Attend a second university visit for assessments of body composition, metabolism, and muscle function.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Habitual Daily Protein Intake
Timeframe: Baseline
Habitual Daily Protein Intake Relative to Body Mass
Timeframe: Baseline
Appendicular Lean Mass
Timeframe: Baseline
Handgrip Strength
Timeframe: Baseline
Peak Knee Extensor Torque
Timeframe: Baseline
Peak Knee Flexor Torque
Timeframe: Baseline
sporadic Inclusion Body Myositis Functional Assessment (sIFA)
Timeframe: Baseline
Activities of Daily Living: Nottingham Extended Activities of Daily Living Scale (NEADL) Total Score
Timeframe: Baseline
Muscle Functional Cross-Sectional Area
Charlotte Emily Linscott, BSc
Timeframe: Baseline
Skeletal Muscle Volume
Timeframe: Baseline