To investigate the effects of simple dietary management and diet combined with exercise capacity-targeted intelligent lifestyle management on improving metabolic indicators in patients with overweight/obesity and metabolic syndrome.
Who can participate
Age range20 Years – 60 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged between 20 and 60 years.
* Overweight or obese, with a Body Mass Index (BMI) ≥ 24 kg/m² and \< 40 kg/m².
* Patients with impaired metabolic parameters regarding glucose, lipids, and blood pressure,meet at least two of the following criteria:
* Central obesity: Waist circumference ≥ 90 cm for males or ≥ 85 cm for females.
* Hyperglycemia: Fasting plasma glucose (FPG) ≥ 6.1 mmol/L, or 2-hour plasma glucose ≥ 7.8 mmol/L during an oral glucose tolerance test (OGTT), and/or currently receiving treatment for previously diagnosed diabetes.
* Hypertension: Blood pressure ≥ 130/85 mmHg, and/or currently receiving treatment for previously diagnosed hypertension.
* Elevated fasting triglycerides (TG): ≥ 1.7 mmol/L.
* Reduced fasting high-density lipoprotein cholesterol (HDL-C): \< 1.04 mmol/L.
Exclusion Criteria:
* History of cardiovascular or cerebrovascular disease, or in the acute phase, including: angina pectoris, myocardial infarction, coronary revascularization surgery, stroke (ischemic or hemorrhagic, including transient ischemic attack), symptomatic peripheral artery disease requiring surgery or diagnosed via angiographic techniques, ventricular arrhythmias, uncontrolled atrial fibrillation, congestive heart failure (New York Heart Association class III or IV), hypertrophic cardiomyopathy, history of aneurysm with diameter ≥ 5.5 cm, or history of aneurysm surgery.
* Malignancy or history of malignancy within the past five years.
* Religio…
What they're measuring
1
metabolic syndrome prevalence
Timeframe: From enrollment to the end of treatment at 3 months and 6 months
Trial details
NCT IDNCT07535333
SponsorChina National Center for Cardiovascular Diseases