CompletedNot Applicable

Virtual Reality-Based Upper Limb Rehabilitation in Chronic Stroke

Spain26 participantsStarted 2022-09-01

Plain-language summary

This randomized controlled study aims to evaluate the effectiveness of non-immersive virtual reality-based rehabilitation using the MindMotion™ GO system compared with conventional occupational therapy for improving upper limb motor function in individuals with chronic stroke. Stroke is a leading cause of long-term disability in adults worldwide, and barriers such as limited access to rehabilitation services, low motivation, and reduced adherence may hinder recovery in the chronic phase. Participants will be randomly assigned to either an experimental group receiving non-immersive virtual reality training or a control group receiving conventional occupational therapy according to standard clinical practice. Both groups will complete two rehabilitation sessions per week for eight weeks, with each session lasting approximately 40 minutes. The study will assess upper limb motor function, performance in activities of daily living, and quality of life. In addition, electroencephalography (EEG) will be used before and after the intervention to explore potential neuroplastic changes associated with rehabilitation. Outcome assessments will be conducted at baseline and at follow-up approximately three months after the initial evaluation. The results of this study may help determine whether non-immersive virtual reality is an effective and accessible tool to enhance rehabilitation outcomes in individuals with chronic stroke.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Participants must meet all of the following criteria: * Age between 18 and 80 years. * Chronic phase of ischemic stroke affecting the dominant hemisphere in the Middle Cerebral Artery territory (more than 6 months and less than 4 years since stroke onset). * Ability to actively extend the wrist at least 20 degrees and extend the fingers at least 10 degrees. * Upper limb muscle strength of the paretic limb ≥2 in the shoulder, elbow, and wrist. * Adequate trunk control. * Adequate vision and hearing to interact with the rehabilitation platform. * Ability to collaborate and follow study procedures. * Meeting safety criteria for Electroencephalography recording. * Signed informed consent. Exclusion Criteria: Participants will be excluded if any of the following conditions are present: * Severe cognitive impairment (Montreal Cognitive Assessment score \<10). * Major depression or emotional disorders associated with severe attention or cooperation deficits that may interfere with hand function. * Severe psychiatric disease. * Severe spasticity in the affected limb (Modified Modified Ashworth Scale ≥3-4). * Aphasia preventing comprehension of verbal instructions. * Visuospatial neglect preventing interaction with the rehabilitation interface. * Participation in other upper limb rehabilitation therapies during the study period. * Severe functional dependency prior to stroke. * History of other strokes occurring after the index stroke. * Any medical condition …

What they're measuring

Upper Limb Motor Function

Timeframe: Baseline and 3 months after baseline.

Trial details

NCT IDNCT07534124

SponsorUniversidad Complutense de Madrid

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-30