Prospective RegIstry for Oncologic Reirradiation (PRIOR-DK)
500 participantsStarted 2026-04-01
Plain-language summary
The study aims to provide a setup for collecting radiotherapy-related toxicity data, loco-regional control, and overall survival data for all Danish cancer patients undergoing reirradiation with high dose intention or with the aim of local tumour control; with the ultimate aim of providing safe reirradiation to a larger group of patients. To build a reirradiation cohort database for future research
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* High dose reirradiation (reirradiation type I or II or repeat organ irradiation delivered with the aim of local control)
Read Danish (for questionnaires + patient information)
Life expectancy due to age and co-morbidity of ≥6 months.
The general condition must be sufficient to tolerate persistent significant side effects
Histological or imaging verified loco-regional recurrence, solitary oligo metastasis or new primary
Age ≥18 years
Signed informed consent, updated annually
Expected follow up physical, by video, by phone or likely contact at a relevant oncological department
Available dose plan(s) from primary (and prior) radiotherapy course(s) (with 3D reconstruction of previous plans, available port film, or drawings). Multiple re-treatments are allowed (new inclusion and baseline registration)
Exclusion Criteria:
* The primary and reirradiation treatments may not be quasi-simultaneous (i.e. the two treatments should be planned independently)
Inability to attend full course of radiotherapy
Purpose of radiotherapy is ONLY palliation of symptoms