ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant Patients (NCT07516314) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant Patients
United States476 participantsStarted 2026-05
Plain-language summary
This study is a phase 2, multicenter, randomized controlled trial to test the application of Acceptance and Commitment Therapy (ACT) in HCT patients.
ACT is an evidence-based cognitive behavioral therapy intervention that emphasizes psychological flexibility and behaviors, helping transplant patients focus on actions that may help maintain adequate physical activity despite physical and emotional discomfort.
Who can participate
Age range18 Years – 80 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Patient Inclusion Criteria:
* Ability of participant to understand this study, and participant willingness to sign a written informed consent. NOTE: Remote / electronic consent via REDCap consenting allowed per IRB policy and approval.
* Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study
* Plan to undergo allogeneic HCT in approximately 30 days
* Males and/or females age 18 - 80 years
* Agreement to adhere to Lifestyle Considerations throughout study duration
* Access to necessary resources for participating in a technology-based intervention (i.e., computer, smartphone, internet access). NOTE: A smartphone will be provided to participants if needed.
* Able to read/write English or Spanish (as we lack trained ACT interventionists in other languages)
Caregiver Inclusion Criteria:
* Ability of participant to understand this study, and participant willingness to sign a written informed consent. NOTE: Remote / electronic consent via REDCap consenting allowed per IRB policy and approval.
* Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study
* Males and/or females age 18-80 years
* Agreement to adhere to Lifestyle Considerations throughout study duration
* Access to necessary resources for participating in a technology-based intervention (i.e., computer, smartphone, internet access). NOTE: A smartphone will be provided to …
What they're measuring
1
Change in Physical Function (Six Minute Walk Test Distance)